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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Chemistry of materials 3 (1991), S. 5-6 
    ISSN: 1520-5002
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 27 (1994), S. 5223-5226 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using the polymerase chain reaction (PCR) technique, we have screened the DNA of 42 patients with Duchenne or Becker muscular dystrophy for deletions within the DMD gene. Two regions within putative deletion “hot spots” of this gene were tested, and deletions were found in 16.6% of patients. The oligonucleotide primers employed in this study initiate the amplification of exon sequences and were used to test the suitability and reliability of PCR in deletion screening and prenatal diagnosis using various numbers of cycles and artificial contamination ratios. We compared our approach with both “multiplex DNA amplification” and Southern blot analysis. A comparative evaluation of currently available techniques is presented.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 55 (1992), S. 119-120 
    ISSN: 1432-0630
    Keywords: 42.60 ; 61.40 ; 68.35
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The formation of nap-type and wall-type structures on laser-irradiated polyimide (PI) films is reported for the first time. These investigations demonstrate that such structures can develop on non-melting polymer surfaces.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1076
    Keywords: Duchenne muscular dystrophy ; Deletion screening ; Prenatal diagnosis ; Polymerase chain reaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe the application of deletion screening by amplification of deletion-prone exons via polymerase chain reaction (PCR) in a family with a sporadic case of Duchenne muscular dystrophy (DMD). No DNA was available from the affected patient who died 12 years beforehand at the age of 18 years. Material obtained prenatally from two male fetuses exhibited an identical deletion. These findings effectivly transformed a sporadic case into a familial case and a numerical carrier risk was substituted by obligate carrier status. Additionally an indirect genotype analysis was replaced by the possibility of direct DNA analysis. Genetic counselling, formerly based upon incomplete data, can now be aided by precise risk assessment.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 23 (1993), S. 223-253 
    ISSN: 0084-6600
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Stimulation of [3H]inositol monophosphate 〈[3H]InsP) formation by ibotenate or trans-1-aminocyclopentyl-l, 3-dicarboxylic acid (t-ACPD) in rat hippocampal slices was enhanced after tetanic stimulation of die Schaffer collaterals projecting to the CA1 region (in vitro) or the perforant pathway projecting to the dentate gyms (in freely moving animals). This effect was observed 5 h (but not 2 h) after long-term potentiation (LTP) induction and was abolished if tetanic stimulation was performed in the presence of specific antagonists of N-methyl-D-aspartate receptors. The delayed increase in excitatory amino acid-induced polyphosphoinositide (PPI) hydrolysis was accompanied by an enhanced responsiveness to norepinephrine, whereas the basal and carbamylcholine-stimulated [3H]InsP formation were unchanged. These results suggest that an increased activity of „metabotropic” glutamate receptors may contribute to the synaptic mechanisms enabling the late expression and or maintenance of LTP. Accordingly, LTP decayed more rapidly (within 5 h) in rats repeatedly injected with LiCl (60–120 mg/kg, i.p., for 10 days), a treatment that led to a reduced efficacy of ibotenate and norepinephrine in stimulating PPI hydrolysis in hippocampal slices.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 19 (1992), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this study was to determine the effect of ultrasonic instrumentation on composite resin restorations lined with glass ionomer cement by measuring the extent of dye penetration at the restoration/tooth interface. Preparations, 2-0 mm in diameter and 2-5 mm in depth, were made with a 331 bur in 96 human molar teeth without a bevel. The teeth were restored with glass ionomer eement liners (Shofu) and one of two types of composite resin (Silux® and P-30®). Half of the samples were ultrasonically instrumented for 10 s. The teeth were immersed in 0-5% methylene blue dye solution and vertieally sectioned. Mieroleakage was scored visually using a seale of 0 to 4. Statistical comparisons were made with X2 analysis and the Marin-Whitney U-test at the F〈0.05 level. Microleakage was significantly different between both resin types (P〈 0-001), and between the lined and unlined resins (P〈 0-001) that were instrumented, particularly in the P-30® restorations. Although P-30® restorations exhibited much less microleakage than Silux®, the use of a glass ionomer liner did not reliably reduce microleakage in either type of material after instrumentation with an ultrasonic device.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 96 (1992), S. 4509-4517 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The Fulton–Gouterman transformation is applied to the dynamical E–e Jahn–Teller problem. This approach leads to an unconventional way of visualizing the exact eigensolutions of the problem. It turns out that in the upper energy region, eigenfunctions with unexpected behavior make their appearance ("exotic states''). They practically have no distortion in the oscillatory subspace, whereas eigenfunctions of large radial oscillatory displacement are found in their immediate energetic neighborhood. In a rough way, these exotic states may be attached to the upper potential sheet of the "Mexican hat'' and furthermore they can be shown to be related to the "Slonczewski resonances.''
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : American Institute of Physics (AIP)
    Physics of Fluids 3 (1991), S. 2371-2377 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The amplification of disturbances developing under conditions of natural transition in the unstable three-dimensional boundary-layer flow on a swept-back flat plate is measured with the aid of hot-wire anemometry. A detailed analysis of the experimental data allows identification of the most amplified instability modes and determination of their growth rates. The results are compared with linear stability theory. Although the amplification process is affected by nonlinearities starting a short distance downstream of the positions where the disturbances become of measurable size, in some essential respects the applicability of linear theory can be examined. It turns out that the initial amplification rates of the stationary instability modes are fairly well predicted whereas the amplification rates of the nonstationary modes are overestimated. A remarkable feature is that the disturbances with the largest amplitudes are not, in every case, the most amplified ones in theory as well as in experiment.
    Type of Medium: Electronic Resource
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