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  • 1
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 5 (1989), S. 1005-1008 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 93 (1989), S. 5966-5969 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 63 (1988), S. 1872-1876 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An active anode plasma source has been developed for use in a magnetically insulated ion diode operated on a 1010-W pulsed power generator. This source uses an inductive voltage from a single turn coil to beak down an annular gas puff produced by a supersonic nozzle. The resulting plasma is magnetically driven toward the radial insulating magnetic field in the diode accelerating gap and stagnates at a well-defined surface after about 300 ns to form a plasma anode layer defined by magnetic flux surfaces. An ion beam is then extracted from this plasma layer by applying a 150-kV, 1-μs pulse to the accelerating gap. Optimization of the timing of the gas puff, the plasma production discharge, and the high voltage pulse has resulted in 1-μs duration 75–150-keV ion beam pulses with 〉100-A/cm2 peak ion current density over an area of about 400 cm2. Up to 5 J/cm2 has been collected by a 4-cm2 calorimeter. The diode impedance history can be varied so that rising, flat, and falling voltage pulse waveforms can be produced. Streak photographs of beamlets impinging on a scintillator and time integrated targets both show beam divergence angles ≤3°. However, under certain operating conditions, large excursions (∼25°) in mean aiming angle on time scales of 20–200 ns are observed.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 119 (1988), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We have examined the localization of DNA replicating cells and EGF receptor-expressing cells in the epidermis of psoriasis vulgaris, a benign hyperproliferative skin disease, and Bowen's disease, a pre-malignant hyperproliferative skin disease, and normal skin. DNA replicating cells were detected by anti-BrdU monoclonal antibody after incubating tissue sections with BrdU, and EGF receptors were detected by the anti-EGF receptor monoclonal antibody B4G7. In normal skin, DNA replicating cells were localized exclusively in the basal and suprabasal layers. EGF receptor expression was observed most strongly in the basal and parabasal layers, but diminished gradually towards the upper squamous layer. In psoriatic skin, DNA replicating cells were also localized in the basal and parabasal layers, but the number of these mitotic cells was about 10 times higher than in normal skin. In this case, more EGF receptors were detected in all viable layers of the epidermis. Apparently normal skin adjacent to psoriasis lesions showed persistent expression of EGF receptors in the upper squamous layer without an increased number of DNA replicating cells in the basal and parabasal layers. In Bowen's disease, DNA replicating cells and EGF receptor expressing cells were distributed in all layers of the epidermis. These findings indicate that the increased production of EGF receptors may be, in part, responsible for the hyperproliferative state of the epidermis and that cells in the upper squamous layer of psoriasis may have lost a mechanism by which EGF receptor expression is diminished thus allowing differentiation. This altered process of EGF receptor production may be involved in the onset of psoriasis vulgaris.
    Type of Medium: Electronic Resource
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  • 6
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    Unknown
    Honolulu, etc. : Periodicals Archive Online (PAO)
    Pacific Affairs. 38:2 (1965:Summer) 179 
    ISSN: 0030-851X
    Topics: Political Science , Sociology , Economics
    Notes: BOOK REVIEWS
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 26 (1969), S. 105-117 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of actinomycin D on the replication of CAM strain of influenza A1 virus was studied in the human conjunctival cell line, clone 1-5C-4. Actinomycin D in a concentration of 0.5 mcg/ml suppressed the virus yield to less than l/1000th of that from the uninhibited culture. When the addition of actinomycin D was delayed, the resistance of the production of virus and viral components to actinomycin D developed progressively in the order of the soluble antigen, hemagglutinin, and the infective virus. The synthesis of virus-specific RNA was demonstrable by the incorporation of tritiated uridine when actinomycin D was added to the culture at 6 hours after infection, but not when it was added at 1 hour after infection. These findings indicated that actinomycin D illhibits influenza virus replication because it inhibits the synthesis of virusspecific RNA and that, however, it does not directly block virus-specific RNA synthesisper se but exerts the inhibitory effect on some event(s) preceding virus-specific RNA synthesis. In FL cells, in which CAM virus undergoes an abortive multiplication cycle, virus-specific RNA was synthesized in the same period after infection and in a similar quantity as in clone 1-5C-4 cells in which complete multiplication occurs.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Wood science and technology 22 (1988), S. 21-32 
    ISSN: 1432-5225
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary Oligoesterification of wood was investigated by alternately adding esterification reactions of wood with maleic anhydride and allyl glycidyl ether. The products obtained consisted of acetone-insoluble and soluble parts. The insoluble parts were novel oligoesterified woods with oligoester chains having polymerizable double bonds. The oligoester chain length showed a tendency to decrease with increase in wood content in feed. The soluble parts were free oligoesters which were not linked with the wood matrix. The products (the oligoesterified wood-containing mixtures), when subjected to hot-pressing in the presence of a peroxide, gave plasticized crosslinked wood boards whose surfaces are smooth, glossy, and plasticlike. In this case, the free oligoesters which were hardening worked as a plasticizer for the wood components and were combined, by the crosslinking, with the oligoesterified woods, resulting in the formation of the network structure. The crosslinked wood boards exhibited outstanding properties in heat distortion temperature (〉165°C) and compressive strength (ca. 1,600–2,300 kg/cm2).
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Wood science and technology 22 (1988), S. 335-344 
    ISSN: 1432-5225
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary Oligoesterification reaction of wood with phthalic anhydride and glycidyl methacrylate (GMA) was investigated. The reaction proceeded smoothly at 90°C. The products obtained consisted of acetone-insoluble and soluble parts. The insoluble parts were novel oligoesterified woods with oligoester chains having methacrylate double bonds. The soluble parts were viscous liquids consisting mainly of free oligoesters not linked with the wood matrix, and contained small amounts of GMA and oligoesterified wood components which were dissolved out. The products (the oligoesterified wood-containing mixtures), when subjected to hotpressing, gave plasticized crosslinked wood boards whose surfaces are smooth, glossy, and plasticlike. In this case, plasticization of wood components and thermal polymerization of the methacrylate double bonds in the oligoester chains occurred simultaneously even in the absence of radical initiator. The soluble parts worked as a plasticizer for the wood components. The crosslinked wood boards exhibited outstanding properties in tensile strength (∼ca. 700 kg/cm2), flexural strength (ca. 900–1030 kg/cm2), and Rockwell hardness (ca. 120).
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 278 (1986), S. 329-334 
    ISSN: 1432-069X
    Keywords: Melanoma metastasis ; Interferon ; Time-dependent suppression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of murine α/β interferon (IFN) on experimental metastasis was investigated using B16-F10 melanoma cells. Since the outcome of metastasis of blood-borne tumor cells is mainly determined within the first 24 h after i.v. inoculation of tumor cells, i.p. injection of IFN was focused on this critical early phase. The inhibition of pulmonary metastases by IFN was found to be maximal when given 3 h prior to tumor cell inoculation, while mice with 24-h and 12-h pretreatment and simultaneous IFN treatment also showed a reduction in metastases, but to a lesser extent. However, mice receiving IFN 2 h after tumor cell inoculation did not show any reduction. Tumor cells cultured for 24 h in IFN-containing medium showed no reduction in metastases. Administration of anti-asialo GMl prior to IFN treatment was found to eliminate the inhibitory effect of IFN 3 h pretreatment. However, natural killer (NK) cell activity in vitro measured at 3 h, 13 h and 24 h after IFN administration was enhanced to the same extent, not paralleling the inhibitory effect on pulmonary metastases. These data indicate that prepared host status against blood-borne tumor cells is established by IFN pretreatment, being maximal when injected several hours prior to tumor cell inoculation, and that this effect is substantially dependent on NK cell activity, though the implication of other factors is not excluded.
    Type of Medium: Electronic Resource
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