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  • 1985-1989  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of amlodipine in renal impairment (1989)
    Springer
    European journal of clinical pharmacology 36 (1989), S. 205-208 
    Details
    ISSN: 1432-1041
    Keywords: amlodipine ; pharmacokinetics ; renal-impairment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Amlodipine was administered as 14 single 5-mg oral daily doses to 27 male subjects with renal function ranging from normal to haemodialysis-dependent. Blood specimens were obtained for measurement of plasma amlodipine concentrations for 24 h following the first dose, for 168 h following the final dose and during daily administration of amlodipine. Amlodipine was well tolerated. Renal impairment had little effect on the pharmacokinetics of amlodipine. The elimination half-life was of the order of 50 h, similar to previously reported values and did not vary with renal function. Steady-state pre-dose concentrations were observed after the ninth dose. Accumulation of amlodipine was not significantly different from that expected on theoretical grounds and did not significantly change with renal function. These results suggest that once daily administration of amlodipine is suitable for all degrees of renal function and that dosage adjustment is not necessary in renal impairment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00609197
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Revised space-group frequencies for organic compounds (1985)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 41 (1985), S. 203-204 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: In a recent paper Mighell, Himes & Rodgers [Acta Cryst. (1983), A39, 737-740] reported the space-group frequency for nearly 30 000 organic compounds in the NBS Crystal Data Identification File [(1982). JCPDS, Swarthmore, PA]. When the frequencies tabulated by Mighell et al. for those space groups that do not contain any operations of the second kind are revised somewhat different results are obtained. (Numbers given by Mighell et al. are given in parentheses.): 75% (75%) of compounds fall into only five space groups: P21/c, 29.2% (36.0%), P212121, 18.8% (11.6%), P\bar 1, 11.1% (13.7%), P21, 10.9% (6.7%) and C2/c, 5.4% (6.6%); 12(16) space groups account for 87% (90%) of the compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010876738500040X
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Surface plasmon dispersion analysis in the metal-oxide-metal tunnel diode (1987)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 62 (1987), S. 1313-1317 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Three peaks corresponding to the ultraviolet, visible, and near infrared were recently observed in the light emission spectra of a metal-oxide-metal (MOM) tunnel diode. This was the first time UV emission was reported at room temperature with a MOM diode, and it was associated with the radiative surface plasmon. Simple dielectric theory predicts the location of the UV peak as well as the others, but is unable to give a complete description of the spectral output. To gain a clearer understanding of the spectral emission, a more comprehensive detailed model of surface plasmon dispersion in the MOM system is presented. The model is very general and includes the effects that different oxides, metals, and their thicknesses have on the dispersion curves. When applied to simpler systems, the model agrees well with the theoretical work of others. Also, associated with the cathode-oxide interface is a nonradiative mode that is found to play a major role in the transition from the visible to UV peaks in the diode's spectra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.339657
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Observation of radiative surface plasmons in metal-oxide-metal tunnel junctions (1986)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 59 (1986), S. 3137-3143 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A peak in the ultraviolet (UV) region of the spectrum of light emitted from metal-oxide-metal (MOM) tunnel junctions has been observed at room temperature. Both the amplitude and wavelength of the peak are sensitive to applied junction bias. The UV peak corresponds to the normal or radiative surface plasmon mode while a visible peak, also present in our spectra and reported in past MOM literature, is due to the tangential or nonradiative mode. The radiative mode requires no surface roughness or gratings for photon coupling. The results show that it is possible to obtain radiative surface plasmon production followed by a direct decay into photons with MOM tunnel diodes. A MOM diode with a double anode structure is found to emit light associated only with the nonradiative mode. The thickness dependence of the UV peak along with the experimental results of the double anode MOM diode and the ratio of the UV peak to visible peak support our contention that the UV light emission is indeed due to the radiative surface plasmon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.336892
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    Paper (German National Licenses)
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