ISSN:
1434-4726
Keywords:
Anti-keratin antibody
;
Palatine tonsil
;
Tonsillar focal infections
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Titers of anti-keratin antibodies (AKA) involving IgG and IgM fractions were determined by a solid-phase enzyme-linked immunosorbent assay (ELISA) and were found to be significantly higher on average in patients with pustulosis palmaris et plantaris (PPP) than in normal controls. Positive rates of IgG-AKA and IgM-AKA in sera of PPP patients were 50% and 66%, respectively. Following tonsillectomies, patients with high IgM-AKA titers that decreased after surgery were found to benefit by a marked improvement in their skin lesions. There was a close relationship between the degree of this improvement in the skin lesions and the changes in IgM-AKA titers after the operation. These results suggest that PPP may be a tonsil-related immunological skin disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00457465
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