ISSN:
1600-0765
Quelle:
Blackwell Publishing Journal Backfiles 1879-2005
Thema:
Medizin
Notizen:
This study was undertaken to investigate the effect of a sanguinarine-containing dentifrice on supragingival and subgingival plaque in response to suggestions that sanguinarine extract has antiplaque activity. Volunteer dental students were randomly assigned to a control or an experimental group. During an initial examination, plaque scores and samples of subgingival plaque were obtained. The students were given oral hygiene instructions and were told to floss once and brush twice daily, using either the experimental (sanguinarine-containing) or control (any other) dentifrice for a period of 1 month, following which they were once more examined. Plaque scores and samples of subgingival plaque were again obtained. Examination of subgingival plaque was performed using a phase-contrast microscope to determine the distribution of bacterial morphotypes. Comparison of the data from the initial examination with that at the completion of the study showed a significant reduction of supragingival plaque within each group. However, there was no significant difference in the amount of supragingival plaque between groups. There were no significant between-group differences for any bacterial morpho-type. It was concluded that sanguinarine extract had no detectable antiplaque activity when used in a dentifrice.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1111/j.1600-0765.1986.tb01462.x
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