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  • 1
    Electronic Resource
    Electronic Resource
    Demonstration of enamel matrix proteins on root-analogue surfaces of rabbit permanent incisor teeth (1977)
    Springer
    Calcified tissue international 24 (1977), S. 223-229 
    Details
    ISSN: 1432-0827
    Keywords: Enamel-cementum-morphology ; Immunocytochemistry ; Biochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The continuously erupting rabbit incisor tooth is normally thought of as having an enamel covered “crown” on its labial surface and a cementum covered “root” on its lingual surface. We have examined both surfaces of continuously erupting rabbit incisor teeth taken from near term embryos by a variety of means, including transmission and scanning electron microscopy, biochemical fractionation, and immunohistochemistry. In all cases, we could detect no qualitative difference in the early extracellular matrices taken from the labial and lingual surfaces of the teeth. Both matrices were shown to be composed of dentin and enamel, although the thickness and geometry of the enamel matrix on the lingual surface was somewhat different from that on the labial surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02223320
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Complement fixing activity in diseased human gingival tissues (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 16 (1981), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Human gingival tissue biopsies were classified as “initial or early” or “established or advanced” periodontal lesions on the basis of the histopathological criteria of Page and Schroeder (1976). They were then examined for the ability to fix complement by the anticomplement immunofluorescence technique which detects fixation of exogenously applied guinea pig complement. Complement fixation was found in association with IgG deposits (detected by immunohistochemical staining) in 80 % of the established and advanced lesion, thus suggesting that it was fixed by immune complexes or aggregated IgG. The complement fixing activity was not associated with IgA or IgM deposits. In contrast, less than 13 % of the initial and early lesions were found to contain such activity. The presence of complement fixing activity was thus found to be significantly correlated with the more advanced as opposed to the earlier stages of periodontal inflammation (p = 0.02 by Chisquare analysis).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1981.tb02019.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    In vivo antiplaque activity of a sanguinarine-containing dentifrice: Comparison with conventional toothpastes (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 21 (1986), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study was undertaken to investigate the effect of a sanguinarine-containing dentifrice on supragingival and subgingival plaque in response to suggestions that sanguinarine extract has antiplaque activity. Volunteer dental students were randomly assigned to a control or an experimental group. During an initial examination, plaque scores and samples of subgingival plaque were obtained. The students were given oral hygiene instructions and were told to floss once and brush twice daily, using either the experimental (sanguinarine-containing) or control (any other) dentifrice for a period of 1 month, following which they were once more examined. Plaque scores and samples of subgingival plaque were again obtained. Examination of subgingival plaque was performed using a phase-contrast microscope to determine the distribution of bacterial morphotypes. Comparison of the data from the initial examination with that at the completion of the study showed a significant reduction of supragingival plaque within each group. However, there was no significant difference in the amount of supragingival plaque between groups. There were no significant between-group differences for any bacterial morpho-type. It was concluded that sanguinarine extract had no detectable antiplaque activity when used in a dentifrice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1986.tb01462.x
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  • 4
    Electronic Resource
    Electronic Resource
    Specificity of gingival plasma cells for bacterial somatic antigens (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 17 (1982), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Human gingival tissue biopsies were classified as “initial or early” or “established or advanced” periodontal lesions on the basis of the histopathological criteria of Page and Schroeder (1976). The percentage of plasma cells in each specimen that could recognize somatic antigens associated with one of four bacterial strains was then determined by incubating frozen sections of the gingiva with rhodamine-labeled bacterial cells. The sections were also briefly incubated with a fluorescein-labeled antibody to human immunoglobulins to facilitate plasma cell detection. Of the bacterial strains tested (Bacteriodes gingivslis, Actinomyces viscosus strains ATCC 27044 and T14–V, and Actinobacillus actinomycetemcomitans). only B. gingivalis was found to bind to a significantly higher percentage of plasma cells in the more advanced lesions as compared with the earlier lesions (16.3 % versus 3.7 %). These results suggest an important role for somatic antigens associated with B. gingivalis in the immunopathogenesis of human periodontitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1982.tb01131.x
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  • 5
    Electronic Resource
    Electronic Resource
    Effects of non-steroidal anti-inflammatory drugs on demineralized bone-induced bone formation (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 27 (1992), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The inhibitory effect of some non-steroidal anti-inflammatory drugs (NSAIDs) on bone resorption is well documented. To explore the effect of NSAIDs on bone formation, we investigated the time course and dose/response characteristics of treatment with various non-steroidal anti-inflammatory drugs (NSAIDs) on ectopic bone formation induced by demineralized bone matrix (DBM) in the rat model. Using biochemical assays, both inhibitory and stimulatory effects on bone formation were found in rats treated with NSAIDs prior to DBM implantation depending on the type and amount of drug administered. There appears to be an enhancement of bone formation for acetaminophen (50 mg/kg), acetylsalicylic acid (50 mg/kg), and ibuprofen (50 mg/kg). Indomethacin (4 mg/kg) and piroxicam (4 mg/kg) had inhibitory effects. Flurbiprofen, on the other hand, did not appear to affect bone formation significantly. In contrast, there was no effect of NSAIDs on bone formation in rats treated with the drugs after implantation of the DBM. It appears that the time course of the drug administration is critical, suggesting that early events in bone formation may be modulated by arachidonic acid metabolites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1992.tb02082.x
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  • 6
    Electronic Resource
    Electronic Resource
    Some effects of cocatalyst structure on the anionic polymerization of ε-caprolactam (1964)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 8 (1964), S. 1363-1369 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: N-Acetyl, N-butyryl, N-stearyl, N-benzoyl, N-4-methoxybenzoyl, and N-4-nitrobenzoyl caprolactams were prepared and used as cocatalysts for the anionic polymerization of caprolactam. The results of these studies indicate that all of the cocatalysts used, except N-acetylcaprolactam, exert a steric effect which lowers both the rate and degree of polymerization. The N-benzoyl derivative appeared to be a slightly better cocatalyst than the N-4-methoxybenzoyl derivative. This may be due to the fact that the N-benzoyl group is the more electron-attracting group. N-4-Nitrobenzoylcaprolactam was unstable under the reaction conditions employed.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1964.070080326
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  • 7
    Electronic Resource
    Electronic Resource
    Some effects of cocatalyst structure on the anionic polymerization of ∊-caprolactam. II.From the theses of R. P. Scelia and S. E. Schonfeld which were submitted in partial fulfillment of the requirements for the degree of Master of Science. (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 11 (1967), S. 1299-1313 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A study of the effect of catalyst (base) concentration and N-acylcaprolactam cocatalyst size and substitution on the fast anionic polymerization of caprolactam indicated that a steric effect due to cocatalyst size exists, and perhaps an electronic effect due to cocatalyst substitution was noted. The rate of polymerization, degree of polymerization, and yield of polymer are related to these effects. It was also noted that at high base concentrations, the rate and degree of polymerization along with the product yields all decrease. These latter observations suggest that reinterpretation of some of the reaction mechanism data may be important if polymer degradation is not an appreciable factor during the reaction.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1967.070110726
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