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  • 1
    Electronic Resource
    Electronic Resource
    Magnetic resonance imaging of children with Duchenne muscular dystrophy (1987)
    Springer
    Pediatric radiology 17 (1987), S. 495-497 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight children representing a spectrum of clinical states of biopsy-proven Duchenne muscular dystrophy (DMD) underwent magnetic resonance (MR) scans to assess the degree of muscular involvement and disease progression. Five muscle groups (neck, shoulder girdle, pelvic girdle, thigh and calf) were evaluated. In each case, involved muscles were clearly demarcated. Image estimates of disease severity by degree of muscle involvement correlated well with clinical staging. In our experience MR is useful for assessment of disease stage, selection of appropriate muscles for biopsy and planning for courses of physical and rehabilitation therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02388288
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  • 2
    Electronic Resource
    Electronic Resource
    Heterogeneity of membrane phospholipid mobility in endothelial cells depends on cell substrate (1985)
    [s.l.] : Nature Publishing Group
    Nature 317 (1985), S. 75-77 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Bovine pulmonary artery endothelial cells (BAEC) were established from primary cultures and grown in Dulbecco's minimal essential medium (Gibco) containing 10% fetal calf serum (Hyclone). We used cells between passages 3 and 10; their endothelial origin was confirmed by the presence of cyto-plasmic ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/317075a0
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  • 3
    Electronic Resource
    Electronic Resource
    Metastatic carcinoma of the spine (1987)
    Springer
    International orthopaedics 11 (1987), S. 345-348 
    Details
    ISSN: 1432-5195
    Keywords: Carcinoma ; Cord compression ; Metastases ; Spine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Une étude rétrospective portant sur 172 patients atteints de métastases osseuses carcinomateuses montre que 54% d'entre eux ont des métastases vertèbrales décelées à la radiographie et à la scintigraphie. Parmi celles-ci, le carcinome mammaire est la tumeur primitive la plus fréquente (30%), suivi par le cancer du poumon (17%), de la prostate (10%) et du rein (9%). La distribution segmentaire des métastases vertèbrales montre que la colonne lombaire est la plus fréquemment atteinte, et qu'il existe une affinité métastatique sélective de certains carcinomes pour des segments vertèbraux particuliers. L'apparition d'un syndrôme de compression médullaire, qui survient dans 30% des cas de dissémination vertèbrale, assombrit significativement le pronostic des ces malades. L'hypernéphrome a une propension marquée à entraîner une compression neurologique (4/8). C'est le segment dorsal qui est le plus exposé à la compression médullaire, secondaire dans 50% des cas à une fracture-luxation du corps vertèbral.
    Notes: Summary In a retrospective study of 172 patients with disseminated carcinoma in the skeleton, 54% were shown by radiography and scintigraphy to have vertebral metastases. Breast carcinoma was the most common primary tumour, occurring in 30% of the patients, followed by lung (17%), prostate (10%) and kidney (9%). The lumbar spine was most often involved and some primary carcinomas showed a predilection for particular spinal segments. Cord compression occurred in 30% of the patients with vertebral spread and was a poor prognostic sign for long-term survival. Hypernephroma was the most common tumour to cause spinal cord involvement. The thoracic segment was the most frequent site of cord compression (43%), and pathological fracture-dislocation was the most common cause (50%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271312
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  • 4
    Electronic Resource
    Electronic Resource
    Metastatic bone disease from occult carcinoma: a profile (1989)
    Springer
    International orthopaedics 13 (1989), S. 119-123 
    Details
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs ont revu les observations de 172 malades porteurs de métastases osseuses, vus entre 1965 et 1985, afin d'apprécier l'aspect général des métastases provenant d'un cancer primitif méconnu. Chez 51 malades (30%) l'origine du cancer primitif n'avait pu être découverte lors du diagnostic de métastase osseuse. Ce groupe était à prédominance masculine, comportant un nombre élevé d'atteintes vertébrales, de compressions médullaires et de fractures pathologiques, et un taux de survie significativement plus court (P〈0,1) comparativement à celui des métastases d'un cancer primitif connu. La localisation du cancer primitif a été découverte dans 33 cas (65%), la plupart du temps à l'autopsie. Le cancer du poumon était le plus fréquemment en cause (52%), alors qu'il n'était responsable que de 7% des cas quand le cancer primitif était connu. Il semble que l'apparition de métastases osseuses d'origine inconnue doive faire évoquer d'emblée la possibilité d'un cancer du poumon. Si le cancer primitif ne peut être découvert il est vraisemblable qu'il siège au niveau du poumon, la probabilité d'un cancer du poumon méconnu, responsable des métastases, étant élevée.
    Notes: Summary To assess the general profile of metastatic bone disease from occult primary carcinoma, the records of 172 patients with skeletal metastases seen between 1965 and 1985 were reviewed. In 51 patients (30%), the origin of the primary could not be identified when bone metastases were first diagnosed. This group were predominantly male with a high incidence of spinal metastases, cord compression and pathological fractures, and a significantly shorter (P〈0.1) survival compared with bony metastases when the primary was known. The site of the primary was established in 33 patients (65%), mostly at autopsy. Lung carcinoma was by far the most common primary tumour in 52% of the cases, while it accounted for only 7% of those with a diagnosed primary. We believe that the onset of bony metastases from an occult source must initially raise the possibility of lung carcinoma. If the primary remains undetected, it appears justifiable to assume it to be in the lung, since the probability of a missed lung tumour being responsible for the metastases is high.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00266372
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  • 5
    Electronic Resource
    Electronic Resource
    159. Die Naht veralteter Meniscusrisse — Bericht über 272 Fälle (1987)
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 824-824 
    Details
    ISSN: 1435-2451
    Keywords: Meniscus suture ; Old torn menisci ; Meniscusnaht ; Veraltete Meniscusläsion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Von 1980 bis 1985 wurden an den orthopädischen Universitätskliniken München und Zürich 287 veraltete Meniscusläsionen bei 280 Patienten durch Naht via Arthrotomie wieder vereinigt. 95% der Patienten (272 Meniscusläsionen) konnten zwischen 6 Monate und 5,5 Jahren postoperativ durch Fragebogen (13%), alleinige klinische Untersuchung (13%), klinische Untersuchung und Arthrographie (69%) oder durch klinische Untersuchung und Arthroskopie (5%) nachuntersucht werden. In 106 Kniegelenken erfolgte isoliert die Meniscusnaht, bei 159 Kniegelenken wurden veraltete Kapselbandschäden mit versorgt. Alter, Geschlecht, Länge des Meniscusrisses, Seitenbezogenheit, Lokalisation des Risses, postoperative Immobilisation, Nachuntersuchungszeitraum und Beschwerdedauer hatten keinen Einfluss auf das Ausheilungsergebnis, jedoch konnte eine Proportionalität zwischen Kniegelenksinstabilität und persistierendem Meniscusriss gefunden werden (p = 0,001). Die Rezidivquote betrug 8%, davon waren die Hälfte klinisch stumme Rerupturen.
    Notes: Summary Between 1980 and 1985, 287 old torn menisci were sutured in 280 patients via arthrotomy in the Orthopaedic University departments of Zurich and Munich. In 95% of the patients (272 meniscus lesions), there was a follow-up between 6 months and 5.5 years postoperatively using questionnaires (13%), clinical examination alone (13%), clinical examination and arthrography (69%), and clinical examination and arthroscopy (5%). Suture of old torn menisci alone was performed in 106 knee joints, whereas in 159 knee joints old ligamentary instabilities were treated operatively as well. We could find no connection between age, sex, length or localization of the rupture, postoperative immobilization, periods of trouble, and postoperative examination. However, there was a correlation between old ligamentary instabilities and persistant meniscus lesions. A recurrence was seen in 8%. Half of the patients with persistant meniscus ruptures, however, had no complaints.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297943
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