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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 65 (1985), S. 305-312 
    ISSN: 1432-0533
    Keywords: Hamster ; Myelin deficiency ; Spinal cord
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A new disorder of central myelination was found in black mutant hamsters showing trembling. The condition was inherited in an autosomal recessive mode. Histologically, a marked myelin deficiency was distributed throughout the central nervous system (CNS), and it was closely related to clinical manifestations observed in the mutants Ultrastructurally, abnormally thin myelin sheaths were observed in all axons with different diameters, and most axons below 1 μm in diameter were unmyelinated in the white matter of the spinal cord. There was no overt evidence of demyelination, but some myelin sheaths showed an aberrant configuration. The numbers of glial cells were not reduced, and there were no striking morphological abnormalities in them. It was suggested that there may be a dysfunction of oligodendrocytes resulting in retarded or defective myelination. This trembling hamsters may be a suitable animal model for the study of normal and abnormal myelinogenesis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 99 (1988), S. 227-233 
    ISSN: 1437-1596
    Keywords: Human blood identification ; Counterimmunoelectrophoresis ; Bloodstains, microprecipitation method ; Blutidentifizierung, Gegenstromimmunoelektrophorese, Mikropräzipitationsmethode ; Spurenanalyse, Blutfleck
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wurden die Empfindlichkeiten mittels der Gegenstromimmunoelektrophorese (GIE), der modifizerten GIE und der Mikropräzipitationsmethode (MPM) zur Identifizierung von menschlichem Blut an einem verdächtigen winzigen Blutfleck (ein Faden mit einer Länge von 2 mm) mit Anti-HbA Serum gemessen und verglichen. Die minimalen Grenzen der positiven Reaktionen erwiesen sich durch GIE als 1:160 verdünntes Blut, durch die modifizierte GIE 1:320 und durch MPM 1:320. Diese positiven Reaktionen wurden nach etwa 1 h vom Untersuchungseinsatz gewonnen. Die festgestellten Empfindlichkeiten mittels GIE und der modifizierten GIE verminderten sich entsprechend der Abname der Menge von Blutfleck, von einer Hälfte bis ein Achtel vom Faden mit einer Länge von 2 mm, während sie bei MPM nicht sanken.
    Notes: Summary A minute bloodstain on a thread 2 mm in length was tested to identify human origin by counterimmunoelectrophoresis (CIE), modified CIE, and microprecipitation method (MPM), using anti-human HbA serum. The detection limits expressed as the highest dilution of human blood on the thread in positive reaction were 1:160, 1:320, and 1:320 in CIE, modified CIE, and MPM, respectively. About 1 h was required to obtain the results. In CIE and modified CIE, the detection limits diminished according to the reduction of the samples from one half to one-eighth of the thread, but not in MPM.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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