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  • 1
    Electronic Resource
    Electronic Resource
    β-adrenoceptor blockade and migraine (1982)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 2 (1982), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Except for propranolol, no other b-blocker has been studied thoroughly in the prophylaxis of migraine. Of those studied, propranolol, atenolol and timolol were shown to be useful in double-blind clinical trials. The mode, or even the site of action of these drugs is unknown. Possible mechanisms of action are peripheral vascular effects, a central action, 5-HT antagonism, an anxiolytic effect and a multifactorial action. The only common property of the successful drugs is lack of partial agonist activity and their profiles do not fully support any of the above hypotheses. Trials of drugs in the prophylaxis of migraine have in general been unsatisfactory due to the difficulty in controlling many variables. b-blockers with differing properties offer an opportunity to define the properties necessary for anti-migraine activity and perhaps shed light on the pathogenesis of migraine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1982.0201033.x
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  • 2
    Electronic Resource
    Electronic Resource
    Electrophilic Bromination of 7-Norbornylidene-7'-Norbornane. The Observation of an Unusually Large Inverse Deuterium Kinetic Isotope Effect (1995)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 117 (1995), S. 8769-8776 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00139a009
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  • 3
    Electronic Resource
    Electronic Resource
    Nuclear magnetic resonance study of acid-base interactions for the chloranil electrode system in acetonitrile (1972)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 76 (1972), S. 246-248 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100646a018
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  • 4
    Electronic Resource
    Electronic Resource
    On the mechanism of aluminum via fill by reflow and forcefill as studied by transmission electron microscopy (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 571-577 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A comparison has been made between the Al via fill mechanisms in both reflow and forcefill processes. Cross-sectional transmission electron microscopy has been used to study the Al transport into the vias as a function of time. Our analysis shows that reflow and forcefill results can be explained by a stress relaxation model. We propose that the transport of aluminum into the vias as a function of time is described by both diffusion and dislocation movement. In the case of reflow at high temperature, the vias may be filled completely, after closure, by high-temperature creep of Al. In the case of forcefill, an additional high stress has been applied which raises the strain levels such to activate the dislocation glide and climb mechanism. The results from detailed investigations of the microstructure by cross-sectional transmission electron microscopy support these new insights. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.369491
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  • 5
    Electronic Resource
    Electronic Resource
    Components of A Jungian Theoretical Orientation (1984)
    Oxford, UK : Blackwell Publishing
    The @journal of analytical psychology 29 (1984), S. 0 
    Details
    ISSN: 1468-5922
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1465-5922.1984.00067.x
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  • 6
    Electronic Resource
    Electronic Resource
    Experiments to Assess the Hydraulic Efficiency of Well Screens (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 21 (1983), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: The hydraulic properties of commercial well screens were investigated to determine which screen design features affected head loss. The test program began with laboratory experiments and continued as a field-scale experiment with the installation of a well field in the Thames Valley Gravel Aquifer.The laboratory experiments indicated that, for all practical purposes, the head loss attributable to all of the screens tested was negligible. The experimental head loss, however, did vary from screen to screen, particularly at high intake velocities, and the screens could be ranked on the basis of their hydraulic efficiencies. This efficiency hierarchy is explained tentatively in terms of the screen construction methods and slot geometry. The field experiments showed that the hydraulic performance of all well screens is independent of screen design provided that the open area of the screen is above about 10%. The field experiments also indicated that the development capacity of a screen in a gravel aquifer is not wholly dependent on screen design, but that progressive development does increase the hydraulic efficiency of a well.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1983.tb00722.x
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  • 7
    Electronic Resource
    Electronic Resource
    Treatment of timber products with gaseous borate esters (1995)
    Springer
    Wood science and technology 29 (1995), S. 385-395 
    Details
    ISSN: 1432-5225
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary Several factors which influence the treatment of timber products with vapour phase preservatives such as borate esters are considered. Gas flow rate through the substrate was found to be a significant factor limiting both preservative penetration and its rate of deposition. A theoretical model of the treatment process was developed and tested experimentally to determine the influence of several factors on the retention and distribution of boric acid. Gas flow into the timber product was influenced by permeability, pressure gradient and substrate moisture content. The implications of the findings are considered with regard to the treatment of wood and wood products with gaseous reagents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00202586
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  • 8
    Electronic Resource
    Electronic Resource
    Treatment of timber products with gaseous borate esters (1998)
    Springer
    Wood science and technology 32 (1998), S. 25-31 
    Details
    ISSN: 1432-5225
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This paper forms a continuation of the work on treatment of timber products with gaseous borate esters. Turner and Murphy (1995) in an earlier paper indicated that gas flow rate into the wood substrate was the principle factor limiting the rate of boric acid retention and the depth of penetration into wood products. The current paper considers the impact of this factor on treatment efficacy and considers experimental work designed to evaluate qualitatively, the impact of proposed modifications to the process. Significant improvements in treatment performance were observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00702557
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  • 9
    Electronic Resource
    Electronic Resource
    MRT-gesteuerte regionale Tiefenhyperthermie (1999)
    Springer
    Der Radiologe 39 (1999), S. 756-763 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter MRT-Bildgebung ; Regionale Tiefenhyperthermie ; Weichteiltumoren ; Knochentumoren ; Key words MRI ; Regional hyperthermia ; Soft-tissue tumors ; Bone tumors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: Regional hyperthermia in combination with chemotherapy or/and radiotherapy is a promising treatment concept for locally advanced, deep-seated tumors. The purpose of the project is the optimization of the therapy using non-invasive, three-dimensional imaging of tissue changes or of the temperature distribution during regional hyperthermia. Methods: MRI offers methods suitable in principle for tissue characterization and MR thermometry. A new MRI-hyperthermia hybrid system has been developed based on an innovative hyperthermia applicator and an open MRI system. Results: After successful testing of the new MRI-hyperthermia hybrid system simultaneous MRI and regional hyperthermia in patients could be accomplished for the first time. At present the T1 relaxation time seems to be a promising parameter for MR thermometry. Conclusion: The first clinical application of the MRI-hyperthermia hybrid system can be regarded as an important step towards the development of regional hyperthermia. This new hybrid system and the MR thermometry methods have to be investigated prospectively in clinical studies.
    Notes: Zusammenfassung Fragestellung: Die regionale Tiefenhyperthermie in Kombination mit Chemotherapie und/oder Radiotherapie ist ein vielversprechendes Behandlungskonzept für lokal fortgeschrittene, tiefliegende Tumoren. Ziel dieses Projektes ist die nichtinvasive, dreidimensionale Darstellung der Gewebsveränderungen und der Temperaturverteilungen während der regionalen Tiefenhyperthermie. Methodik: Die Magnetresonanztomographie bietet prinzipiell geeignete Methoden für die Gewebecharakterisierung und für die MR-Thermometrie. Auf der Basis eines innovativen Hyperthermieapplikators und eines offenen MR-Tomographen wurde ein neues MRT-Hyperthermie-Hybridsystem entwickelt und erprobt. Ergebnisse: Nach der erfolgreichen Erprobung des neuen MRT-Hyperthermie-Hybridsystems an Phantomen und Probanden konnte erstmals am Patienten eine simultane MR-Bildgebung und Tiefenhyperthermie durchgeführt werden. Die T1-Relaxationszeit erscheint nach unseren derzeitigen Forschungsergebnissen ein vielversprechender Ansatz für die MR-Thermometrie bei 0,2 T zu sein. Schlußfolgerung: Der erstmalige klinische Einsatz des MRT-Hyperthermie-Hybridsystems kann als wichtiger Meilenstein für die Gesamtentwicklung der regionalen Tiefenhyperthermie bezeichnet werden. Das neue Gerät und die unterschiedlichen MRT-Verfahren, insbesondere die der MR-Thermometrie, müssen nun in klinischen Studien untersucht werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050572
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  • 10
    Electronic Resource
    Electronic Resource
    A Cadmium(II) Complex of Creatinine, [Cd(C2H3O2)2(C4H7N3O)2].0.5H2O (1996)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 52 (1996), S. 3043-3045 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270196009833
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