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Distribution of lysozyme in synovial tissue of patients with osteoarthritis and rheumatoid arthritis demonstrated by different enzyme histochemical methods (1982)

Fritz, P. ; Müller, J. ; Braun, U. ; [et al.]

Springer

Rheumatology international 2 (1982), S. 41-47

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ISSN: 1437-160X

Keywords: Mononuclear phagocytes ; Rheumatoid arthritis ; Osteoarthritis ; Enzyme histochemical demonstration of lysozyme ; Polymorphonuclear cells

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Lysozyme-producing cells were analysed by enzyme histochemistry in paraffin sections of synovial tissue of 60 patients with rheumatoid arthritis (RA) and 20 patients with osteoarthritis (OA). For lysozyme detection three enzym histochemical systems — peroxydase-antiperoxydase, alkaline phosphatase and biotin-avidin — were used in parallel experiments. Lysozyme was found to be produced by polymorphonuclear cells, mononuclear phagocytes and part of synovial lining cells. All types of lysozyme-producing cells were increased in RA compared with OA. Subgrouping of RA synovitis according to histomorphological criteria allowed the demonstration of an inverse relationship between the number of lysozyme-producing cells and the grade of proliferation of fibroblasts, called mesenchymoid transformation by Fassbender [19]. The different methods of lysozyme detection differed in specificity and sensitivity. The immunoenzymatic staining of lysozyme allows specific and quantitative evaluation of phagocyting cells in RA and OA.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00541270

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An analytical solution for axisymmetric tunnel problems in elasto-viscoplastic media (1984)

Fritz, P.

New York, NY [u.a.] : Wiley-Blackwell

International Journal for Numerical and Analytical Methods in Geomechanics 8 (1984), S. 325-342

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ISSN: 0363-9061

Keywords: Engineering ; Engineering General

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Architecture, Civil Engineering, Surveying , Geosciences

Notes: An analytical solution is presented for the time-dependent stresses and displacements in plane strain around a circular hole when it is loaded by an axisymmetric internal and far-field pressure. The material is assumed to be elasto-viscoplastic with dilatant plastic deformations according to a non-associated flow rule. Strain softening is considered by a modified St. Venant slider which is characterized by Mohr-Coulomb yield conditions for both the peak and the residual strengths.

Additional Material: 10 Ill.