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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 46 (1980), S. 59-70 
    ISSN: 1432-1246
    Keywords: Environment ; Lead ; Free erythrocyte porphyrin ; Smoking ; Biological quality guide for lead ; Umwelt ; Blei ; freies Erythrocyten-Porphyrin ; Rauchen ; biologische Überwachung auf Gefahrdung durch Blei
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden Blutbleikonzentrationen (PbB) and FEP-Werte von 1423 bzw. 673 50jährigen Männern aus einer westdeutschen Großstadt (Köln) bestimmt. Der geometrische Mittelwert der PbB-Werte beträgt 12,8 μg/100 g, der Mittelwert der FEP-Werte 35,3 μg/100 ml Erythrocyten. Probanden, die überwiegend im Bereich der Produktion and Verarbeitung tätig waren, wiesen im Durchschnitt höhere PbB-Werte auf als die im Bereich von Büro, Verwaltung, Schule etc. Tätigen. Zigarettenraucher hatten signifikant höhere PbB-Werte als Nie-Raucher. Die höchsten mittleren PbB-Werte traten im Innenstadtbereich Bowie in drei stark industrialisierten Stadtteilen auf; in Stadtrandgebieten wurden deutlich niedrigere Werte gefunden. In dem untersuchten PbB-Bereich (3,5–56,4 μg/100 g) konnte kein statistisch signifikanter Zusammenhang zwischen erhbhten PbB- and FEP-Werten nachgewiesen werden. Die Bedeutung der PbB-Bestimmung als primarer Screening-Test zur biologischen Überwachung der Bevölkerung auf Gefahrdung durch Blei wird hervorgehoben.
    Notes: Summary Blood lead levels (PbB) and FEP-levels were measured in 1423 and 673 50-year-old males, respectively, from Cologne, a large West German city. The mean PbB value was 12.8 μg/ 100 g and the mean FEP was 35.3 μg/100 ml erythrocytes. Subjects working in production lines or in processing plants had higher PbB values than subjects working as employees and officers in administration, management, schools etc. Cigarette smokers had significant higher PbB values than non-smokers. The highest mean PbB values were found in the city centre as well as in three highly industrialized areas. PbB values were smaller in suburban areas. Within the range of PbB levels studied (3.5–56.6 μg/100 g), no statistically significant relationship between PbB and FEP could be demonstrated. The importance of PbB as a primary test for the biological screening of the population for lead is emphasized.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 48 (1981), S. 375-389 
    ISSN: 1432-1246
    Keywords: Thallium exposure ; Cement factories ; Biological monitoring ; Thallium levels in urine ; Thallium levels in hair ; Health effects of low-level chronic thallium exposure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to assess the degree of thallium exposure in a population living around a thallium emitting cement plant in a small city in North-West Germany thallium levels in 24 h urine samples of 1,265 subjects and in hair samples of 1,163 subjects were determined. Urinary thallium levels in two groups of subjects living in an urban and a rural area of West Germany were determined for reference. As compared to these subjects the population living around the cement plant exhibited obvious signs of increased thallium intake. The mean urinary thallium concentration was 2.6 μg/1 and ranged up to 76.5 pg/1. In contrast, the mean urinary thallium levels of the two reference groups were 0.2 and 0.4 μg/1, respectively. Hair thallium levels of the population living around the cement plant were also markedly increased (mean: 9.5 ng/g). The major route of the population's increased intake of thallium was found to be the consumption of vegetables and fruit grown in private gardens in the vicinity of the cement plant. As was shown by chemical analyses vegetables and fruit grown in these gardens were contaminated by thallium-containing atmospheric dust fall-out caused by emissions of the cement plant. The pulmonary route of uptake as well as other sources did not seem to play a significant role in the population's exposure to thallium. Polyneuritic symptoms, sleep disorders, headache, fatigue and other signs of psychasthenia were found to be the major health effects associated with increased thallium levels in urine and hair. No positive correlation was found between the thallium levels in hair and urine and the prevalence of skin alterations, hair-loss and gastro-intestinal dysfunctions.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 51 (1983), S. 231-252 
    ISSN: 1432-1246
    Keywords: Tooth-lead concentrations ; Blood-lead concentrations ; Children ; Intelligence ; Perceptual-motor integration ; Behavior ratings ; Sociohereditary background ; Multiple regression-analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Results from neuropsychological tests, collected under double-blind-precautions, were evaluated for 115 schoolage children (mean age: 9.4 years) living in a lead smelter area (Stolberg, FRG). Tooth-lead concentrations (PbT) from shed incisor teeth as measures of longtime lead-exposure were available for these children (x = 6.16 ppm; range: 1.9–38.5 ppm), and for 83 of them blood-lead concentrations (PbB) were available as well (x = 14.3 μg/dl; range: 6.8-33.8 μg/dl). The following functional capacities were tested: intelligence (German WISC), perceptual-motor integration (Göttinger Formreproduktionstest = GFT, Diagnosticum for Cerebralschüdigung = DCS), reaction performance (Wiener Determinationsgerät), finger-wrist tapping-speed, and repetitive cancellation-performance (Differentieller Leistungstest). In addition standardized behavior ratings were obtained by the examiners, the mothers, and the teachers. Multiple stepwise regression-analysis (forced solution) was calculated for outcome-variables and Pb-tooth, including age, sex, duration of labor, and socio-hereditary background as covariates. Significant (P〈 0.05) or near-significant (P〈 0.1) association was established between Pb-tooth and GFT-performance (errors), reaction-performance (false reactions), and four behavioral dimensions as rated by the mothers, namely distractability, restlessness, lack of information, and wasting of time; the proportion of explained variance never exceeded 6%, however, No significant association was found between PbT and WISC verbal-IQ after the effects of “socio-hereditary background” had been eliminated, although there was still a tendency for high level-children (PbT 〉 10 ppm) to be inferior to low level-children (PbT ≦ 4 ppm) by 4.6 IQ-points after correction for confounding. There was a near-significant, inverse relationship between fingerwrist tapping-speed and Pb-blood. The results are discussed within the framework of attention-deficit disorder, and compared to neurobehavioral Pb-effects from animal-experiments, which provide suggestive evidence for a causal relationship between developmental lead-exposure and certain neurobehavioral deficits.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 50 (1982), S. 139-151 
    ISSN: 1432-1246
    Keywords: Tooth lead levels ; Blood lead levels ; Current lead exposure ; Long-term lead exposure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Lead concentrations were measured in the deciduous teeth (incisors) of 302 children living in a lead-smelter area in the FRG (Stolberg, Rheinland) and of 86 children living in a nonpolluted rural area (Gummersbach, Bergisches Land). Blood lead levels were determined in 83 of the children living in the lead smelter area. On average, tooth lead levels of children living in the smelter area (mean: 6.0 μg/g; range: 1.49–38.5 μg/g) were significantly higher than those of children living in the rural area (mean: 3.9 μg/g; range: 1.6–9.4 μg/g). Blood lead levels were 6.8–33.8 μg/100 ml (mean: 14.3 μg/100 ml). Children of lead workers had on average higher tooth lead and blood lead levels than children of people who were not lead-workers. Tooth lead levels increased with increasing duration of residence in the lead-smelter area and with the degree of local environmental pollution by lead, as indicated by the lead content of the atmospheric dust fall-out around the children's homes. The correlation coefficient of tooth lead vs blood lead was 0.47. The intra-individual variability of tooth lead levels was low (r=0.86), and tooth lead levels of brothers and sisters were similar (r=0.75), suggesting that tooth lead may be used as a representative and reliable indicator of long-term lead exposure.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 15 (1980), S. 1140-1146 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract From the experiments during steady state creep of V3Si single crystals at T=1280 to 1400° C and σ=1 to 7×107 Pa, activation volumes, 10 to 70 b 3, and activation enthalpies, 2 to 11 eV, have been derived. With deviation from stoichiometric composition a hardening effect has been experimentally established. It is suggested that the rate controlling process was due to dislocation glide and dynamic recovery by dislocation climb.
    Type of Medium: Electronic Resource
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