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  • 1980-1984  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Cathepsin-B activity in otosclerosis (1983)
    Springer
    European archives of oto-rhino-laryngology and head & neck 238 (1983), S. 123-125 
    Details
    ISSN: 1434-4726
    Keywords: Otosclerosis ; Stapes footplate ; Cathepsin B
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cathepsin-B activity was determined fluorimetrically in the otosclerotic stapes footplate, the stapes superstructure, normal temporal cortical bone, and os frontale osteoma. Measurements with a synthetic substrate made determinations in individual samples possible. The cathepsin-B activity in the otosclerotic stapes footplate was one order of magnitude higher than that of the superstructure, which was not affected by the disease. The cortical bone and the superstructure displayed similar activities, as did os frontale osteoma and otosclerosis. The high lysosomal proteinase activity appears to be closely connected to the otosclerotic bone resorption process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00454303
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Synthesis of 6-deoxy-6-fluoro-L-ascorbic acid (1980)
    Springer
    Cellular and molecular life sciences 36 (1980), S. 1138-1139 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 6-Deoxy-6-fluoro-L-ascorbic acid has been synthesized in 5 steps starting from 2,3-4,6-di-O-isopropylidene-2-keto-L-gulonic acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01976086
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Increase of corticotropin-releasing factor staining in rat paraventricular nucleus neurones by depletion of hypothalamic adrenaline (1984)
    [s.l.] : Nature Publishing Group
    Nature 310 (1984), S. 140-141 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In addition to CRF, it has been suggested that catecholamines acting at central and/or peripheral sites are involved in regulating the release of ACTH2'12"15. In this regard, Seybold et al.16 suggested that catecholamines tonically inhibit vasopressin and neurophysin release from terminals in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/310140a0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Light and electron microscopic localization of substance P-like immunoreactivity in the cerebral ganglion of locust with a monoclonal antibody (1982)
    Springer
    Histochemistry and cell biology 75 (1982), S. 123-131 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The occurrence of substance P-like immunoreactivity was studied in the locust brain at light and electron microscopic level using monoclonal IgG fraction to substance P. Small immunoreactive perikarya have been found beside the medial neurosecretory cells in horizontal brain sections. Widespread immunoreactivity was also observed in the protocerebral neuropil notably in the central body and bordering on the corpora pedunculata. The reaction endproduct appeared as fine, more or less round particles in the central body, and as coarse varicosities and wavy fibres bordering the peduncles. The roundish particles probably represent nerve terminals, while the wavy fibers correspond to neural processes. In the vicinity of the β lobe immunoreactivity was not observed. Electron microscopically, a number of immunoreactive terminals were found in the protocerebral neuropil. The reaction endproduct was accumulated mostly in large dense core granules/average diameter 80 nm/however reaction endproduct was also observed on the external surface membranes of clear vesicles and mitochondria. Our results suggest the widespread occurrence of a substance-P immunoreactive neuropeptide in the cerebral ganglia of the migratory locust.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00492539
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    Paper (German National Licenses)
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