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Housing Pathways and Stratification: Some Evidence from a British National Survey (1984)

Sullivan, O. ; Murphy, M. J.

Cambridge : Cambridge University Press

Journal of social policy 13 (1984), S. 147-165

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ISSN: 0047-2794

Source: Cambridge Journals Digital Archives

Topics: Political Science , Sociology

Notes: AbstractFive principles determining movement in the housing market relating to tenure, social class and fertility status were suggested by Payne and Payne (1977) on the basis of a small-scale study in Aberdeen. Analysis of a large-scale nationally-representative survey containing full housing and maternity histories suggests that some of these principles require modification at the national level. For example, movement into and between tenures, although heavily influenced by demographic and socio-economic factors, is not as rigid as the Aberdeen study suggested. The interaction of social class, age at marriage and childbearing patterns is assessed. Finally, changes over time in these relationships and the long-term effects on final family size and tenure are discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1017/S0047279400013477

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The kinetics of hematopoietic stem cells during and after hypoxia (1984)

Loeffler, M. ; Herkenrath, P. ; Wichmann, H. E. ; [et al.]

Springer

Annals of hematology 49 (1984), S. 427-439

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ISSN: 1432-0584

Keywords: Hematopoiesis ; Stem cells ; Mathematical model ; Hypoxia ; Posthypoxia

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary A previously described mathematical model of the hematopoietic stem cell system has been extended to permit a detailed understanding of the data during and after hypoxia. The model includes stem cells, erythroid and granuloid progenitors and precursors. Concerning the intramedullary feedback mechanisms two basic assumptions are made: 1) The fraction “a” of CFU-S in active cell cycle is regulated. Reduced cell densities of CFU-S, progenitors or precursors lead to an accelerated stem cell cycling. Enlarged cell densities suppress cycling. 2) The self renewal probability “p” of CFU-S is also regulated. The normal steady state is described by p=0.5, indicating that on statistical average each dividing mother stem cell is replaced by one daughter stem cell, while the second differentiates. Diminished cell densities of CFU-S or enlarged densities of progenitors and precursors induce a more intensive self renewal (p〉0.5), such that the stem cell number increases. The self renewal probability declines (p〈0.5) if too many CFU-S or too few progenitors and precursors are present. The model reproduces bone marrow data for CFU-S, BFU-E, CFU-C, CFU-E, 59 Fe-uptake and nucleated cells in hypoxia and posthypoxia. Although the ratio of differentiation into the erythroid and granuloid cell lines is kept constant in the model, a changing ratio of CFU-E and CFU-C results. The model suggests that stem cells and progenitor cells are regulated by a regulatory interference of erythropoiesis and granulopoiesis.