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  • 1980-1984  (7)
  • 1
    Electronic Resource
    Electronic Resource
    Anaesthesia in the morbidly obese (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 38 (1983), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Seventy morbidly obese patients presented for upper abdominal surgery; 17% had pre-existing cardiovascular disease and 23% pre-existing respiratory disease. Twenty-eight patients received general anaesthesia, plus narcotic analgesia postoperatively, and 42 general anaesthesia plus thoracic epidural analgesia intra- and postoperatively. Aspects of anaesthetic management are discussed and compared with previous similar reports. Doses of local anaesthetic for induction of epidural analgesia were less than those for the non-obese but doses of local anaesthetic for maintenance of epidural analgesia were similar to those in non-obese patients. Patients who had thoracic epidural analgesia required less volatile anaesthesia than the group who had general anaesthesia and narcotic analgesics. Postoperative respiratory complications were more common in patients with pre-existing cardiovascular and respiratory disease, and occurred less frequently in patients who had thoracic epidural analgesia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1983.tb12249.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Anomalous resistance changes following application of the neurotransmitterl-Glutamate in insect muscle (1982)
    Springer
    Journal of comparative physiology 148 (1982), S. 281-285 
    Details
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Bath application ofl-glutamate, to larval dipteran muscle, at concentrations between 10−6 and 10−4 M will cause a depolarisation of the muscle membrane potential associated with an increase in muscle input resistance. At concentrations above 10−4 M there is usually a transient decrease in input resistance preceding the resistance increase. l-aspartate at concentrations above 10−5 M causes membrane depolarisations which are always associated with an increase in muscle input resistance. The pharmacology of the receptors regulating membrane depolarisations associated with increases in input resistance has been compared with the receptors gating synaptically activated cation channels and found to show significant differences in sensitivity to various ligands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00619134
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Glutamate as the transmitter at fast and slow neuromuscular junctions of larval diptera (1981)
    Springer
    Journal of comparative physiology 144 (1981), S. 139-143 
    Details
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Excitatory postsynaptic currents (EPSCs) produced by stimulating either the fast or slow motor axon to the bodywall muscles of larval sheepfly, are reduced by 60% in the presence of 2 × 10−4 M L-glutamate. L-aspartate at 2 × 10−4 M is without effect on either the fast or slow EPSC. Extracellularly recorded slow EPSCs are also reduced by iontophoresis of L-glutamate onto the active site. Iontophoresis of L-aspartate has no effect on the slow EPSC. These results are discussed in relation to a possible transmitter role for glutamate and aspartate at fast and slow excitatory neuromuscular synapses of the bodywall muscles of larval sheepfly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00612807
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Dinoflagellate origin for sedimentary 4α-methylsteroids and 5α( H )-stanols (1984)
    [s.l.] : Nature Publishing Group
    Nature 308 (1984), S. 439-442 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Dinoflagellates are major primary producers in the oceans7,8, differing from other classes of both marine and lacustrine algae with respect to the dominance of 4a-methylsterols among their sterol components and the uniqueness of certain of these 4a-methylsterol structures. As the principal sterol ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/308439a0
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Ultrastructural demonstration of glucose 6-phosphatase in cerebral cortex (1981)
    Springer
    Histochemistry and cell biology 72 (1981), S. 107-111 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A two-stage fixation technique has been developed to obtain morphological preservation and retention of glucose 6-phosphatase (G6-Pase) activity for its demonstration in rat cerebral cortex. The technique was then employed to localize the enzyme in the cortex where it produced a dense reaction over the well developed granular endoplasmic reticulum cisternae in nerve cells and oligodendrocytes which contrasted with a thin reaction in astrocytes. Other membranous organelles showed no reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00496785
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Ultrastructural study of enzymes in reactive astrocytes: Clarification of astrocytic activity (1982)
    Springer
    Journal of molecular histology 14 (1982), S. 311-321 
    Details
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Enzymes in reactive astrocytes of the corebral cortex were examined at the ultrastructural level in an attempt to resolve some conflicting aspects of astrocytic activity. Correlations between morphological and enzyme changes after injury established that the apparent increase in oxidative enzyme activity was exclusively mitochondrial and not an artefactual reaction product resulting from anoxic cellular damage. Pronounced glucose-6-phosphatase activity within cisternae of an increased amount of the granular endoplasnie reticulum was related to increased glycogen. Further evidence from acid phosphatase activity indieated that astrocytes played a minimal role in phagocytosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01041223
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Neuronal and oligodendrocytic response to cortical injury: Ultrastructural and cytochemical changes (1984)
    Springer
    Journal of molecular histology 16 (1984), S. 165-178 
    Details
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A needle wound was made in the adult rat cerebral cortex. Responses of neurons and oligodendrocytes at the site of injury were followed over a period of 450 days and correlations made between morphological and enzyme cytochemical changes to clarify some phenomena previously unresolved. Evidence from acid phosphatase activity in degenerating neurons showed no increase in the number of cytochemically stained lysosomal profiles nor changes in the subcellular localization of the acid phosphatase reaction product. Our observations indicated that the majority of dying neurons were not digested by their own acid phosphatase ‘autodigestion’ but by the process of heterodigestion. The time-course study revealed that not all the traumatized neurons were eliminated but some persisted permanently in an attenuated ‘atrophic’ state. The atrophic neurons were small in size with low cytoplasmic-nuclear ratios and exhibited low levels of glucose-6-phosphatase and cytochrome oxidase activities. The acid phosphatase activity was slightly increased as evidenced by cytochemically stained hypertrophic Golgi cisternae and a slight increase in the number of lysosomes. The low level of enzyme activities, concerned with carbohydrate metabolism reflected the low metabolic activity in atrophic neurons whilst an increase in Golgi-lysosomal enzyme activity suggested some anabolic process necessary for their survival. Oligodendrocytes displayed only minor changes in morphology, and their glucose-6-phosphatase and cytochrome oxidase activities were normal, suggesting that these cells have little or no involvement in the repair of a cerebral wound. The absence of significant changes in lysosomal acid phosphatase activity indicated a minimal role, if any, of oligodendrocytes in the process of phagocytosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01003547
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    Paper (German National Licenses)
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