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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 2132-2134 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Ferromagnetism at room temperature has been found in Mn/C/Si films prepared by sequential deposition of these elements at a substrate temperature about 360 °C by vacuum evaporation. The saturation magnetization increases rapidly with the carbon quantity, and it is about 250 emu/cc for a film with a nominal structure of Mn(6 nm)/C(0.5 nm)/Si(6 nm). The magnetization measurements at low temperatures show that the magnetic moment per ferromagnetic Mn atom corresponds to more than 1.2 Bohr magnetons. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 84 (1998), S. 1493-1498 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The anomalous and ordinary Hall resistivities for Fe16N2 (saturation magnetization 4πMs: 29 kG at room temperature) and Fe–N martensite (24.8 kG) films have been measured in the temperature range from 30 to 300 K and compared with pure Fe (21 kG) films. All films were epitaxially grown on GaAs(001) substrates by molecular beam epitaxy. The saturation anomalous Hall resistivity ρAS for Fe16N2 at 300 K was 4.0×10−7 V cm/A which was much higher than the values for Fe–N martensite (1.9×10−7 V cm/A) and Fe (1.5×10−7 V cm/A). Also the anomalous Hall constant RA at 300 K for Fe16N2 was 1.5×10−11 V cm/A G, which was much higher than the values for Fe–N martensite (0.8×10−11 V cm/A G) and Fe (0.7×10−11 V cm/A G). Such results are consistent with a much larger magnetic moment for Fe16N2. To investigate the consequences of the giant magnetic moment for Fe16N2 as compared with Fe–N martensite and Fe, the temperature dependences of ρAS and RA were measured. The values of ρAS and RA decreased monotonically with decreasing temperature for Fe16N2, Fe–N martensite and Fe. In the temperature range from 30 to 300 K, the ρAS value for Fe16N2 was much higher than the values for Fe–N martensite and Fe. This originated from the larger thermal fluctuation of the magnetization for Fe16N2. The striking features of Fe16N2 magnetism were its giant magnetic moment and its large thermal fluctuation of the magnetic moment. The electrical resistivity at room temperature for Fe16N2 was around 30 μΩ cm as compared with 10 μΩ cm for Fe. The difference was due mainly to the difference in the residual resistivities. The electrical resistivity for Fe16N2 decreased monotonically with decreasing temperature, which is normal for a metallic material. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 27 (1976), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Activity of cholesterol ester hydrolase localized almost exclusively in the myelin sheath (Eto & Suzuki, 1973a) was greatly affected by exogenous lipids added to the assay mixture. With isolated myelin as the enzyme source, phosphatidylserine was most effective in stimulating the activity. Other phospholipids were less effective. Efhanolamine phospholipid was slightly inhibitory and lysolecithin was strongly inhibitory. Differences in the fatty acid composition did not appear to account for such different effects. Glucosylceramide, galactosylceramide and digalactosylceramide were stimulatory while sulfatide, ganglioside and its asialo-derivative were inhibitory. Saturated fatty acids were generally stimulatory while corresponding unsaturated acids were strongly inhibitory. In order for exogenous lipids to be effective they had to be added to the assay mixture as free dispersion. When heat-inactivated myelin was used as the lipid source, no effect was observed, while equivalent amounts of a whole white matter lipid mixture was effective. Although phosphatidylserine was the most effective activator among the lipids tested, it could not completely replace sodium taurocholate present in the standard assay system. When isolated myelin was stored frozen, the activity of the enzyme declined gradually in the standard system without additional lipids. The stimulating effect of phosphatidylserine was greater for such partially inactivated enzyme sources, although it did not completely restore the activity to that of fresh preparations. When myelin was fractionated into basic protein, proteolipid protein and the high molecular weight acidic protein (Wolfgram) fractions, the last fraction contained most of the recovered activity. However, Wolfgram protein was less active than the intact myelin when assayed without additional lipid. The addition of phosphatidylserine completely restored the activity of this partially delipidated preparation.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 28 (1977), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— The cholesterol ester hydrolase of rat brain, localized almost exclusively in the myelin sheath, has been solubilized from the acidic high-molecular-weight protein fraction of purified myelin. Solubilization required both high ionic strength and an amphoteric detergent, Miranol H2M. Solubilized preparations with apparent purification factors of 300–500 fold over the starting homogenate still contained approx 25% lipid but were retarded on the Sephadex G-200 column. The enzyme was reversibly precipitated when the concentration of either Miranol H2M or KCI was lowered below certain critical levels. The soluble enzyme was characterized for the pH optimum, linearity against incubation time and enzyme protein, and apparent Km. Activity was dependent on the presence of exogenously added lipid. Phosphatidylserine at optimum concentrations stimulated the hydrolytic activity 25-Fold. Effects of other lipids, bile salts, cations, heating and potential inhibitors were examined. β-Naphthyl oleate was a competitive inhibitor but both β-naphthyl acetate and cholesteryl butyrate were non-competitive inhibitors. These results suggested a heterogenous nature of the rat myelin cholesterol ester hydrolase, possibly with different specificities with respect to the chain length of the acyl group of substrates.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 27 (1976), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —Recent clinical and morphological evidence established that adrenoleukodystrophy is a distinct X-linked genetic disorder. Fatty acid compositions of lipids in the brain, adrenal and serum from seven patients were examined. Cholesterol esters of both brain and adrenal contained substantial proportions of fatty acids longer than C22 (11.8–41.9% of total in the brain and 13.4-34.8% of total in the adrenal), while cholesterol esters from normal and pathological control specimens contained very little. These very long chain fatty acids were generally saturated in brain cholesterol esters but significant amounts of unsaturated long chain fatty acids were also present in adrenal cholesterol esters. The long chain fatty acids showed bell-shaped distribution with C25 or C26 at the peak. Ganglio-sides from patients’white matter also showed increased proportions of very long-chain fatty acids, up to 50% of the total. Qualitatively similar but much milder fatty acid abnormalities were also found in galactosylceramide of the brain. On the other hand, fatty acids and fatty aldehydes of brain glycerophospholipids, adrenal free fatty acids, triglycerides and glycerophospholipids were not abnormal. Furthermore, serum cholesterol esters from two patients did not show the long-chain fatty acid abnormality found in brain and adrenal cholesterol esters. Sequential extractions with acetone and hexane established that the characteristic birefringent material in the brain and adrenal is indeed cholesterol esters with very long chain fatty acids. This type of fatty acid abnormality has not been described in other pathological conditions and may well represent the unique biochemical abnormality that is directly related to the fundamental genetic defect underlying adrenoleukodystrophy.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 50 (1995), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A relationship between cardiac output and the onset time of neuromuscular blockade administered into a peripheral vein was evaluated in 41 adult patients. Anaethesia was induced with midazolam and fentanyl and maintained with intermittent doses of fentanyl and 66% nitrous oxide in oxygen. After immobilisation of the forearm in a splint, the ulnar nerve in the other arm was stimulated supramaximally every 10 s and the adduction force of the thumb was recorded. The times from administration of vecuronium 0.08mg.kg-1 to first and 95% depression of twitch response was 82.4(18.0) s and 191.7(33.5) s (mean, SD), respectively. A significant correlation between cardiac index and the onset time of blockade was observed. This study demonstrated that the rapidity of the onset of paralysis in the adductor pollicis muscle after vecuronium injection into a peripheral vein is clearly related to cardiac output.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 19 (1995), S. 282-284 
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Nous avons entrepris des recherches sur la relation entre l'ostéoporose de la colonne vertébrale et l'arthrose du genou au moyen de l'absorptiométrie à rayons X et de la radiographie standar sur 82 femmes sélectionnées au hasard (l'âge moyen est de 77 ans). La densité minérale de l'os (BMD=»Bone Mineral Density«) de la colonne lombaire a été évaluée par l'absorptiométrie. Nous avons évalué les informations provenant des radiographies des genoux pour classer l'arthrose en 2 groupes: »Normal« et »Evolue«. La BMD du groupe type »Evolue« était bien supérieure à celle du groupe type »Normal« (p〈0.01).
    Notes: Summary We investigated the relation between osteoporosis of the spine and osteoarthritis of the knee using dual energy X-ray absorptiometry of the lumbar spine to measure bone mineral density and radiographs of the knee in 82 randomly selected females (mean age 77.5 years). Radiographs of the knee were divided into a normal and severe group. The bone mineral density of the severe group was significantly more than that of the normal group.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-5233
    Keywords: Gastric inhibitory polypeptide ; Truncated glucagon-like peptide-1 ; Incretin ; Sulfonylurea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gastric inhibitory polypeptide (GIP) and truncated glucagon like peptide-1 (tGLP-1) are potent gastrointestinal insulinotropic factors (incretin), mostly released after a meal or ingestion of glucose in man and animals. To investigate whether sulfonylurea (SU) affects the secretion of incretin, the modulation of plasma GIP and tGLP-1 levels following glucose ingestion in non-insulin-dependent diabetic type 2 patients with or without SU therapy was studied. A 75-g oral glucose tolerance test (OGTT) was carried out on 9 healthy subjects (controls) and 18 patients with non-obese type 2, 9 of whom were treated by diet alone (NIDDM-diet) and the other 9 with SU (glibenclamide 2.5 mg or gliclazide 40 mg) once a day (NIDDM-SU). Plasma GIP was measured by radioimmunoassay (RIA) with R65 antibody, and GLP-1 was measured by RIA with N-terminal-directed antiserum R1043 (GLP-1NT) and C-terminal-directed antiserum R2337 (GLP-1CT). Following OGTT, plasma glucose, GIP, GLP-1NT, and GLP-1CT in type 2 patients increased more markedly than in controls, despite the lower response of insulin. However, there were no significant differences in plasma levels of these peptides between the NIDDM-diet and NIDDM-SU groups. Therefore, it is unlikely that SU is involved in the high response of GIP and GLP-1s to OGTT in type 2 patients.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 171-174 (Oct. 1999), p. 469-476 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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