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  • 1
    Electronic Resource
    Electronic Resource
    Interference between anti-HLA antibodies and chlorpromazine (1976)
    [s.l.] : Nature Publishing Group
    Nature 260 (1976), S. 532-533 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Five healthy volunteers were selected on the basis of their HLA types from our HLA reference panel. Three were HLA-A1 positive and two were negative for the same antigen. Each subject was typed many times in different typing sessions and tested with the antisera used in this work. The types were: ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/260532a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Letter to the editor (1978)
    Springer
    European journal of clinical pharmacology 13 (1978), S. 463-464 
    Details
    ISSN: 1432-1041
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00566327
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Plasma and intracellular kinetics of lithium after oral administration of various lithium salts (1977)
    Springer
    European journal of clinical pharmacology 12 (1977), S. 59-63 
    Details
    ISSN: 1432-1041
    Keywords: Lithium salts ; gastrointestinal absorption ; plasma and intracellular kinetics ; affective disorders
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Five healthy volunteers were treated orally with lithium carbonate, sulphate, or chloride. There were no significant differences in area under time-concentration curves, half-lives, total body clearance or apparent distribution volumes between the various salts, either in plasma or in the RBC compartment. The carbonate salt did show a higher RBC/plasma distribution ratio than the other salts, which might possibly imply greater therapeutic effectiveness of this salt. Some considerations on the tolerability of various lithium salts are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00561406
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Plasma renin activity in primary and secondary depression (1977)
    Springer
    European archives of psychiatry and clinical neuroscience 224 (1977), S. 313-318 
    Details
    ISSN: 1433-8491
    Keywords: Primary and secondary depression ; Plasma renin activity ; Noradrenergic system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Plasma renin activity (PRA), both in supine and standing position, was investigated in primary and secondary depressed patients. After orthostatic stimulation (standing position) primary depressed patients showed PRA values significantly lower than did those with secondary depression. The authors stress the importance of the peripheral sympathetic system in the control of renin release and discuss the data obtained in the light of some evidence in the literature indicating a possible impairment of transmitter turnover in central and peripheral noradrenergic synapses in the pathogenesis of primary depression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341613
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    d-Cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label study (1994)
    Springer
    Journal of neural transmission 95 (1994), S. 105-111 
    Details
    ISSN: 1435-1463
    Keywords: NMDA receptor ; glycine ; cycloserine ; schizophrenia ; PCP-psychosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary D-cycloserine, a partial agonist at the strichnine-insensitive glycine site of the NMDA receptor complex, was tested as adjuvant treatment to conventional neuroleptics in chronic schizophrenic volunteers. The drug was administered, o.a.d., at the daily dose of 250 mg for six weeks. Mental status outcome measures were completed at the end of each week of treatment. The major finding was a deteriora of the patients' clinical condition, specifically of their psychotic symptoms. These preliminary results are discussed among others in view of d-cycloserine pharmacologic properties and recent findings on the interaction between NMDA agonists and dopamine system. This study, finally, suggests the need for a controlled dose-finding trial to establish the activity and a therapeutic “window” of this drug in schizophrenia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01276429
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    Paper (German National Licenses)
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