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  • 1
    Electronic Resource
    Electronic Resource
    Trapping of labile cobalt(III) complexes. Characterization of the perchloratopentaamminecobalt(III) ion (1975)
    s.l. : American Chemical Society
    Inorganic chemistry 14 (1975), S. 2864-2865 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50153a059
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  • 2
    Electronic Resource
    Electronic Resource
    Synthetic polypeptide antigens of defined geometry (1977)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 99 (1977), S. 8491-8498 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00468a018
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Histocompatibility typing by cellular radioimmunoassay (1978)
    Springer
    Immunogenetics 7 (1978), S. 201-211 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A quantitative cellular radioimmunoassay (CRIA) for histocompatibility typing is described. Chicken red blood cells (RBC) were incubated in microtiter plates with specific anti-MHC (B) alloantisera and the alloantibody bound measured indirectly by a second binding step with125I-labeled rabbit anti-chicken IgG. The assay is objective, highly consistent, and three to four orders of magnitude more sensitive than conventional hemagglutination assays. The new CRIA was used to detect minor subpopulations of cells in artificial cell mixtures; as few as 1% of relevant cells were easily detected. Erythrocyte chimerism was induced following the injection of B2/B2 chicken embryos with B15/B21 embryonic stem cells. Five weeks after hatching, erythrocyte chimerism was precisely quantitated by comparing the reaction of RBC from the putative chimeras with artificial cell mixtures using specific anti-B15/B21 alloantisera. The percent varied from 13–40% in 13 chimeric animals. The new CRIA was also used for the sensitive detection of tumor-specific antigens on a T-cell lymphoma. An unexpected finding was that anti-B15 alloantibody bound almost as well to B15/B21 heterozygous RBC as to B15/B15 homozygous cells, suggesting that either the concentration or the steric arrangement of B15 alloantigen at the erythrocyte surface may not conform to conventional expectations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01844008
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  • 4
    Electronic Resource
    Electronic Resource
    MHC control of T lymphocyte-macrophage interactions (1979)
    Springer
    Immunogenetics 9 (1979), S. 33-43 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Identity at the major histocompatibility complex (MHC) of primed T cells and macrophages was essential for the development of a T cell proliferative response to Purified Protein Derivative of tuberculin (PPD) in the presence of macrophage-associated antigen and potential allogeneic effects were eliminated by the use of one-way fetal liver chimeras as a T cell source. By contrast, such MHC restriction could not be shown for the T cell—macrophage interaction when antigen was present in soluble form. It was found that the proliferative response of primed (responder × nonresponder) F1 T cells to the Ir-gene controlled antigen, TNP-18 [Glu-Tyr-Lys (TNP) (Glu-Tyr-Ala)5], could only be restored by responder macrophages with bound antigen, while both responder and nonresponder macrophages reconstituted the response to soluble TNP-18. Supernatants from cultured responder or nonresponder macrophages could at least partially replace viable macrophages in the latter case. These results argue for two distinct antigen presentation mechanisms, depending on the physical state of the antigen rather than its chemical nature: one involves recognition of antigen in association with MHC-coded determinants and shows H-2 restriction, while the other, mediated by soluble factors and antigen, does not.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01570391
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  • 5
    Electronic Resource
    Electronic Resource
    Isolation and characterization of a virus (RL 1) infective on Rhizobium leguminosarum (1978)
    Springer
    Archives of microbiology 119 (1978), S. 263-267 
    Details
    ISSN: 1432-072X
    Keywords: Rhizobium ; Virus ; Morphology ; One step growth ; General characterization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A virus (RL 1) that infects Rhizobium leguminosarum was isolated and studied. The virus has phagelike morphology; it has a hexagonal head and a long, flexible, noncontractile tail with a baseplate. The edgeto-edge diameter of head is 760 Å. The tail is 1515 Å long and 115 Å wide. RL 1 is stable at 4° C in distilled water, with only 20% loss in the titer after one month storage. It does not require any ion for stability, and is stable between pH 6.0 and 8.0. The virus is composed of two components; one is thermal sensitive and the other is relatively thermal resistant. Adsorption and ‘one step growth’ experiments under normal growth conditions showed a slow adsorption rate (0.82×10-9 cm3 min-1) followed by a 90 min latent period. The burst size was approximately 100 virus particles per cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00405405
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  • 6
    Electronic Resource
    Electronic Resource
    A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension (1988)
    Springer
    European journal of clinical pharmacology 34 (1988), S. 21-24 
    Details
    ISSN: 1432-1041
    Keywords: felodipine ; metoprolol ; hydrochlorothiazide ; hypertension ; blood pressure ; adverse effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Seventy-six uncomplicated hypertensive patients treated in General Practice, whose seated diastolic blood pressure (Phase V) (dBP) remained ≥95 mmHg after a minimum of 4 weeks treatment with metoprolol 50 mg b.i.d. as antihypertensive monotherapy, were randomized to receive the selective ‘calcium antagonist’ felodipine 5 mg b.i.d. or hydrochlorothiazide 12.5 mg b.i.d. in addition to metroprolol 50 mg b.i.d. The trial duration was 8 weeks, the dose of the felodipine or hydrochlorothiazide being doubled after 4 weeks if ‘control’ of BP (dBP 〈90 mmHg) was not achieved on the initial doses. Over the trial period of 8 weeks, felodipine reduced dBP from 102 to 85 mmHg and hydrochlorothiazide from 101 to 91 mmHg; the dBP reduction in the felodipine group was greater than that in the hydrochlorothiazide group (17 vs 9 mmHg) and the attained dBP lower in the felodipine group. About half of the patients in each group required the higher dose. Both regimes were effective and well tolerated. In the dosages used, felodipine was a slightly more effective antihypertensive drug than hydrochlorothiazide when added to metoprolol. There was no apparent difference in the tolerability of the two regimes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01061411
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  • 7
    Electronic Resource
    Electronic Resource
    High-resolution diffuse X-ray scattering study from nearly perfect silicon single crystals (1979)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 35 (1979), S. 286-295 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: High-resolution measurements of diffuse X-ray scattering (DXS) have been made at and above room temperature around 111, 333, 444 and 555 reciprocal lattice points (relps) using highly collimated Mo Kα1 and Cu Kα1 radiations with the specimen set in (1, -1, 1) symmetrical Bragg geometry. The distribution of DXS intensity around different relps has shown that at temperatures up to at least 573 K the contribution of thermal DXS to the observed DXS is very small. This is apparently due to the high value of the Debye temperature (640 K) of silicon. A remarkable feature of these results is that for the same value of the scattering vector |K*| the DXS intensity is different for the parallel and antiparallel orientations of K* relative to R*. The amount of anisotropy varied from sample to sample and depended on the thermal history of the specimen. This and the other features show that the observed DXS is predominantly due to point defects and their aggregates. A typical size parameter for the aggregates is 3000 to 10 000 Å.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739479000607
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  • 8
    Electronic Resource
    Electronic Resource
    STUDIES ON THE PREPARATION AND NUTRIENT COMPOSITION OF BULGUR FROM TRITICALE (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 44 (1979), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Bulgur of acceptable quality was prepared from two commercially available cultivars of triticale by boiling 10 min and cooking for 3 min or 10 min at 15 psi and 120°C. Moisture contents of 32-41% were needed to achieve a desirable level of gelatinization of starch. Compared to triticale whole meal, bulgur had almost similar amounts of protein, amino acids and gross energy but lower amounts of crude fat, thiamine, riboflavin, folic acid, vitamin E, calcium, iron, copper, phosphorus, manganese, zinc, potassium, sodium and magnesium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1979.tb03809.x
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  • 9
    Electronic Resource
    Electronic Resource
    DIFFERENTIAL LABELING OF JUVENILES A Multivariate Analysis (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Criminology 13 (1976), S. 0 
    Details
    ISSN: 1745-9125
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Law
    Notes: Prior studies and commonsense definitions of the decision-making process suggest that the ascriptive power of the commitment offense, gravity of the commitment offense, psychiatric characteristics of the offender, and the social identity given off by the offender's family would be causally related to variance in the deviance label, i.e., decisions to commit to a mental hospital rather than to a corrections institution. Case records from both settings were analyzed for traces of the decision. However, controlling for each of the alternative variables fails to eliminate the strong relationship between intensity of the offender's prior career of delinquent behavior and the formal deviance label qua type of commitment. The multivariate path model suggests that delinquency intensity and type of commitment are the two most important determinants of mental classification.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-9125.1976.tb00681.x
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  • 10
    Electronic Resource
    Electronic Resource
    Kinetics of Water Sorption by Soybean and Pigeonpea Grains (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 52 (1987), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Kinetics of liquid water sorption by soybean (Glycine max) and pigeonpea (Cajanus cajan) seeds was studied at several temperatures. The data could be accurately correlated in terms of an empirical model involving a single rate constant. The temperature dependence of the rate constant followed Arrhenius relation. Swelling of grains due to water sorption was slightly less than the volume of water imbibed. This loss related to the energy of activation of the water sorption process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1987.tb05874.x
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