ISSN:
1432-0533
Keywords:
Rat
;
Protein deprivation
;
Neocortex
;
Vessels
;
Morphometry
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The postnatal vascular growth in the neocortical area 18 of normal and pre- and postnatally protein-deprived rats was examined. For control rats the specific length, the specific surface and the volume fraction of vessels increased rapidly between 7 and 20 days of age. Thereafter, only a minor increase was seen. In protein-deprived rats there was no increase in the specific length of vessels between 7 and 10 days of age and this variable was still reduced at 30 days of age compared to controls. This reduction was due to a decrease in the specific length of thin vessels (Ø〈8.25 μ) whereas the specific length of wider vessels was not affected by the protein deprivation. There were no significant differences in the specific surface or volume fraction of vessels between control and protein-deprived rats. These findings indicate an adaptive increase in luminal diameter of vessels in the protein deprived rats during postnatal development. At 90 days of age no significant differences between vascular variables of control and protein-deprived rats were seen.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00717035
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