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  • 1
    Electronic Resource
    Electronic Resource
    The dependence of coronary collateral blood flow on regional vascular resistances (1979)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 308 (1979), S. 265-272 
    Details
    ISSN: 1432-1912
    Keywords: Vasodilator agents ; Vascular resistance ; Coronary circulation ; Collateral circulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A method was applied in anesthetized dogs enabling the measurement of regional resistances up to and behind the start of collaterals and the collateral resistance. The studies show that peripheral coronary pressure, i.e. perfusion pressure of the collaterals, can change when the ratio of pre- and post-collateral resistance alters. Drugs can influence collateral blood flow not only by directly effecting the collaterals but also by altering collateral perfusion pressure. Glyceryl trinitrate given in minor doses improved collateral blood flow by directly dilating the collaterals and also by increasing collateral perfusion pressure. Higher doses did not improve collateral flow due to a decrease of collateral perfusion pressure. A stealphenomenon occurred in some cases. Adenosine and verapamil had no direct influence on the collateral resistance. Verapamil given in small doses increased perfusion pressure slightly but not enough to improve collateral blood flow. High doses of verapamil, like low doses of adenosine, had no significant influence on collateral perfusion pressure and collateral blood flow. Adenosine given in high dosage led to a diminution of collateral flow by decreasing collateral perfusion pressure, i.e. a steal-phenomenon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501392
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  • 2
    Electronic Resource
    Electronic Resource
    On the range of α-adrenergic regulation of coronary vascular resistance (1979)
    Springer
    Basic research in cardiology 74 (1979), S. 456-466 
    Details
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Zur Abschätzung der α-adrenergen Regulationsbreite am Koronargefäßsystem wurden folgende Untersuchungen durchgeführt: bei 15 narkotisierten Hunden wurde der Ramus circumflexus der linken Kranzarterie kanüliert und mit einem über der Norm liegenden Druck so perfundiert, daß der koronarvenöse Sauerstoff-druck nicht unter 40 mmHg abfiel. Einflüsse eines variablen Perfusionsdrucks und der metabolischen Komponente der Regulation der Koronardurchblutung waren somit weitgehend ausgeschaltet. Ferner wurden 15 isolierte, isovolumetrisch arbeitende Meerschweinchenherzen nachLangendorff perfundiert. Zur Stimulation bzw. zur Blockade von α-Rezeptoren wurden Xylometazolin bzw. Phentolamin intrakoronar gegeben. Xylometazolin führte am isolierten Herzen und am Herzen in situ zu einer Zunahme des Gefäßwiderstandes. Bei maximaler Dosierung kommt es am narkotisierten Hund zu einer Zunahme des Widerstandes auf 200%, das entspricht einer Abnahme der Leitfähigkeit auf 50%. Diese Wirkung ist durch Phentolamin vollständig blockierbar. Phentolamin hatte am isolierten Herzen keine signifikante Wirkung. Am Herzen in situ bewirkte es bei maximaler Dosierung eine Widerstandssenkung auf ca. 60%, was eine Steigerung der Leitfähigkeit auf ca. 170% bedeutet. Die α-adrenerge Regulationsbreite beträgt am narkotisierten Hund in unseren Experimenten also, setzt man die Ausgangslage gleich 100%, für den koronaren Widerstand ca. 60% bis 200% und für die Leitfähigkeit ca. 50% bis 170%.
    Notes: Summary In order to obtain an estimate of the range of α-adrenergic resistance regulation in the coronary vascular system, the following studies were performed: in 15 anesthetized dogs the circumflex coronary artery was cannulated and perfused with above-normal constant pressure so that coronary venous oxygen tension never fell below 40 mmHg. Thus, it was possible to eliminate the influence of the metabolic factor regulating coronary resistance. Furthermore, 15 isolated isovolumetrically working guinea-pig hearts were perfused according to the Langendorff method. Stimulation, resp. blockade, of α-receptors was achieved by administering xylometazoline, resp. phentolamine. Xylometazoline increased coronary resistance in both the isolated and the insitu heart. Administering maximum doses to the anesthetized dog led to an increase in resistance to about 200%. This is equivalent to a reduction of conductance to about 50%. Phentolamine produced no significant effects in the isolated heart. Maximum dosage administered to the heart in situ led to a resistance decrease to about 60%, equivalent to an elevation of conductance to about 170%. If we let control values of coronary resistance and conductance be equal to 100%, our experiments showed α-adrenergic regulation of coronary resistance to range from about 60% to 200% and conductance to range from about 50% to 170%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01907640
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  • 3
    Electronic Resource
    Electronic Resource
    Dechema-Monographien Bd. 78: Moderne Verfahren der Oberflächenanalyse. Herausgeg. v. D. Behrens u. K. Fischbeck. Verlag Chemie GmbH, Weinheim/Bergstr. 1975. 1. Aufl., 306 S., zahlr. Abb. u. Tab., Ln. DM 57,75 f. Mitglieder d. DECHEMA u. d. Mitgliedsvereine d. Europ. Föderation f. Chemie-Ingenieur-Wesen, DM 72,20 f. Nichtmitglieder (1975)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 47 (1975), S. 533-533 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330471207
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  • 4
    Electronic Resource
    Electronic Resource
    Methods of Surface Analysis Bd. 1. Von A . W. Czanderna. Elsevier Scientific Publishing Comp., Amsterdam-Oxford-New York 1975. 1. Aufl., 481 S., zahlr. Abb. u. Tab., Kunstleder Dfl. 150,-. (1976)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 48 (1976), S. 502-502 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330480539
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  • 5
    Electronic Resource
    Electronic Resource
    Darstellung von Chloro-aqua-Komplexen des Indium(III) und Röntgenstrukturanalyse von [InCl4(H2O)2][S4N3] - einem Tetrachloro-cis-diaqua-Komplex des Indium(III) (1975)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 415 (1975), S. 193-201 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthesis and X-Ray Structure Determination of [InCl4(H2O)2][S4N3] - a Tetrachloro-cis-diaqua Complex of Indium(III)The compounds [InCl4(H2O)2][S4N3] (I) and In2Cl8H2O(S4N3)2 (II) were synthesized and the structure of the former determined by x-ray methods. The compound crystallizes in the space group D2h16-Pnam, the unit cell dimensions are a = 19.473 ± 0.003 Å, b = 6.183 ± 0.003 Å, c = 10.814 ± 0.003 Å. Least squares refinement has reached R = 4.9%.
    Notes: Die Verbindungen [InCl4(H2O)2][S4N3] (I) und In2Cl8H2O(S4N3)2 (II) wurden dargestellt und die Struktur der ersteren mittels Röntgenstrukturanalyse bestimmt. Die Verbindung kristallisiert in der Raumgruppe D2h16 - Pnam mit den Gitterkonstanten a = 19,473 ű 0,003 Å, b = 6,183 ± 0,003 Å, c = 10,814 ± 0,003 Å. Die Verfeinerung nach der Methode der kleinsten Quadrate ergab einen R-Wert von 4,9%.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19754150302
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  • 6
    Electronic Resource
    Electronic Resource
    Die Kristall- und MolekülStruktur von S4N4·2C7H8Anmerkung b. d. Korr.: Die Struktur ist inzwischen auch von anderer Seite veröffentlicht (Griffin u. Sheldrick, Acta Crystallogr. B31, 895 (1975)). Die Publikation unserer Ergebnisse scheint trotzdem sinnvoll, da sie wesentlich genauer sind. (1132 gegenüber 338 Reflexen, R-Wert 3,9 gegenüber 8,8% und damit kleinere δ-Werte, H-Atome aus Differenzfouriersynthese und nicht nur geometrisch lokalisiert.) (1976)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 420 (1976), S. 155-158 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Crystal and Molecular Structure, of S4N4 · 2C7H8The structure of the title compound has been determined from threedimensional X-ray data. Crystals are monoclinic, with unit cell dimenions a = 16.532 Å, b = 8.563 Å, c = 10.880 Å, β = 103.2°, space group C2h6—C2/c and Z = 4. Least squares refinement, by use of 1132 independent reflections measured on a diffractometer has reached 3.9%.In the S4N4·2C7H8 molecules the organic components are linked to two sulfur atoms of the S4N4, ring each.
    Notes: Die Struktur von S4N4 · 2C7H8 wurde röntgenographisch bestimmt. Die Verbindung kristallisiert monoklin, in der Raumgruppe C2h6—C2/c, mit a = 16,532 Å, b = 8,563 Å, c = 10,880 Å, β = 103,2° und Z = 4. Die Verfeinerung nach der Methode der kleinsten Quadrate ergab einen R-Wert von 3,9%.Die beiden Bicyclopentadien-Molekeln sind an je 2 Schwefelatome des S4N4-Ringes gebunden.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19764200208
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