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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 22 (1977), S. 41-47 
    ISSN: 1432-0827
    Keywords: 45Calcium ; Immobilization ; Osteoporosis ; Parathyroid glands ; Thyroparathyroidectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract In order to study the role played by the thyroid and the parathyroid glands in the development of osteoporosis induced by immobilization, 153 male adult Sprague-Dawley rats allocated in two groups were used. The animals of one group were thyroparathyroidectomized; those of the other group were left intact. Each group was then divided into two subgroups; in one the right hind leg of the animals were immobilized by an elastic adhesive bandage. The animals were observed for varying periods of time up to 16 weeks. Studies of bone mass and45Ca accretion rate of the right and left femur and tibia were performed in all animals. The results indicate that disuse osteoporosis occurs in rats in the virtual absence of the thyroid and parathyroid glands. The bone loss of the immobilized femur and tibia was less pronounced in thyroparathyroidectomized rats compared to intact rats. The uptake of45Ca in bone treated by immobilization as compared to the non-immobilized bone was found to be increased to the same proportion in thyroparathyroidectomized and in intact rats. The calcium-accretion rate of non-immobilized bone was lower in thyroparathyroidectomized than in intact rats. The observations indicate that in the rat the parathyroid and thyroid hormones influence the rate of bone turnover and thereby the rate of development of disuse osteoporosis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 27 (1979), S. 161-164 
    ISSN: 1432-0827
    Keywords: Osteoporosis ; Ovary ; Rat ; Vitamin D
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Fifty adult female rats were used to study the effect of 1-alpha-hydroxyvitamin D3 (1α-OH-D3)on bone after oophorectomy. The experimental period was 6 months. At the end of the experiment the femurs and the tibias were investigated for bone mass and composition. Significant signs of osteopenia occurred as a result of oophorectomy. The treatment with 1α-OH-D3 induced only minor changes in blood chemistry but increased bone mass significantly. The findings support the view that 1α-OH-D3 may be a valuable tool in the treatment of osteoporosis resulting from ovarian insufficiency.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 276 (1976), S. 167-177 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A non-relativistic perturbation method of Brueckner-Goldstone type is used to calculate the hyperfine interactions in the lowest2 S and2 P states of the Li-like systems, Li, Be+, B2+, C3+, N4+, O5+ and F6+. The effect of the polarization of the closed shell is treated to all orders of perturbation, while the correlation effect is calculated in the lowest order, i.e. in the third order of the perturbation expansion. Experimental data are at present available only for Li, Be+ and F6+, and the agreement with the calculated values is in these cases very good, usually within the experimental uncertainties. This implies that the predictions made in the remaining cases should be quite reliable, which may simplify the experimental determination of these quantities. Theoretical values are also given for the quadrupole interaction, which can be used to determine the nuclear quadrupole moments, when accurate experimental information becomes available.
    Type of Medium: Electronic Resource
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