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  • 1970-1974  (1)
  • 1965-1969  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Absolute Configuration of the Prostaglandins (1966)
    [s.l.] : Nature Publishing Group
    Nature 212 (1966), S. 38-39 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IT has been reported1 that the enzyme system which converts all-cis 8,11,14-eicosatrienoic acid into prostaglan-din E! (PGEJ also reacts with lids, 14cis-eicosadienoic acid yielding ll-hydroxy-12£rans,14c^s-eicosadienoic acid (I). A small amount of this acid has now been prepared by ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/212038a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prostaglandins (1965)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biochemistry 34 (1965), S. 101-108 
    Details
    ISSN: 0066-4154
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Chemistry and Pharmacology , Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.bi.34.070165.000533
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Use of mass spectrometry for the carbohydrate composition and sequence analysis of glycosphingolipidsThe results of the present work were presented at the Ninth International Congress of Biochemistry, Stockholm, Sweden, 1st to 7th July 1973. (1974)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 1 (1974), S. 49-56 
    Details
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Mass spectrometry has been applied for a detailed structural characterization of glycosphingolipids. Methylated and methylated plus reduced glycolipids (amide groups of ceramide and amino sugars were reduced to the corresponding amines) were found the most useful derivatives. Molecular weight ions [M - 1] were not obtained for methylated lipids with more than four sugar units, but were easily obtained for reduced derivatives, so far with six sugars. Spectra of reduced derivatives showed very abundant ions containing the complete carbohydrate and the fatty acid, allowing a conclusion to be made concerning the carbohydrate composition (ratio of hexose and hexosamine and sialic acid). In addition, conclusive information was obtained for the carbohydrate sequence, including branching of the chain. By a combined use of both derivatives the long chain base and fatty acid composition was also evident. Spectra are discussed for a synthetic monoglycosylceramide, the Forssman glycolipid hapten (pentaglycosylceramide) and two gangliosides (a triglycosylceramide and a pentaglycosylceramide). The mass spectrum of the Forssman glycolipid provides the first conclusive evidence for two amino sugars in the terminal disaccharide of the molecule.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200010111
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Die Prostaglandine (1965)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 77 (1965), S. 445-452 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Prostaglandine, die in vielen Geweben zahlreicher Tierarten vorkommen, sind lipoidlösliche C20-Carbonsäuren. Sie enthalten einen fünfgliedrigen Ring, eine Oxo- und zwei Hydroxygruppen (oder drei Hydroxygruppen), außerdem eine bis drei Doppelbindungen. Die Strukturaufklärung gelang durch eine Kombination chemischer, radiochemischer und physikalischer Methoden mit Gaschromatographie und Massenspektrometrie. Im Organismus bilden sich die Prostaglandine aus essentiellen Fettsäuren. Die Prostaglandine stimulieren die glatte Muskulatur und wirken auf den Fettstoffwechsel ein.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19650771003
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    The Prostaglandins (1965)
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 4 (1965), S. 410-416 
    Details
    ISSN: 0570-0833
    Keywords: Prostaglandins ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Prostaglandins occur in many animal species and tissues. They are C20-carboxylic acids contining one five-membered ring, one keto group, two or three hydroxy groups, and one to three C=C double bonds. Their structures were elucidated by chemical, radiochemical, and physical methods in combination with gas chromatography and mass spectrometry. The prostaglandins are biosynthesized from essential fatty acids. By their action smooth muscles are stimulated and lipid metabolism is affected.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/anie.196504101
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