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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 145 (1974), S. 29-40 
    ISSN: 1432-0568
    Keywords: Reptiles ; CNS ; Development ; Cell proliferation ; H3-thymidine autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Early ontogenetic events in the brain of a lizard, Lacerta sicula, were investigated by means of H3-thymidine autoradiography. Varying dynamic properties—beginning, duration, and end of the proliferating activity, dynamics of the generation cycle—of the matrix zones of different regions and areas of the brain were observed. The main interest was focused on the rhombencephalon, where a distinct heterochronism of proliferation was described for different systems and nuclear groups. Eye muscle nuclei, the trigeminal system, and the hypoglossal nucleus arrive earliest (stage day 1/2–1 1/2). The vestibular and the cochlear system cease their proliferation at stage day 2 1/2 and stage day 3 1/2 respectively. Their proliferation is very rapid. In contrast, the sensory regions of the VIIth, IXth, and Xth nerves and the tegmental regions show a slow, long-lasting proliferation. The great difficulties for embryologic and experimental approach in reptiles are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 80 (1973), S. 179-188 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs analysent 124 cures de chimiothérapie associant vinblastine, procarbazine, cyclophosphamide et méthyl-prednisolone réalisées chez 90 malades atteints de maladie de Hodgkin. Ce traitement, appliqué à des malades hospitalisés, dure en principe trois semaines. L'intolérance, surtout hématologique (leucocytose inférieure à 2000μl) a conduit à abréger la cure dans près de la moitié des cas, mais, rapidement réversible, elle n'a gêné la réalisation d'une irradiation ultérieure que dans deux cas sur 81. Pour 101 cures interprétables, on a observé 10 échecs non totaux, 88 rémissions partielles dont 32 inférieures à 50% et 56 supérieures à 50% et 3 rémissions complètes. Un seul échec a été enregistré chez les 51 malades vierges de traitement. La place de ce traitement dans la stratégie du traitement de la maladie de Hodgkin est discutée et son intérêt souligné en tant que moyen pratique et efficace.
    Notes: Summary Ninety patients with Hodgkin's disease have received 124 courses of chemotherapy with vinblastine, procarbazine, cyclophosphamide and methyl-prednisolone. The treatment is given during a period of 2–3 weeks to hospitalized patients. The main toxicity is haematological and the course is stopped when the leucocytosis is to 2000μl or less. This chemotherapy has allowed a subsequent irradiation in all but 2 among 81 cases. For 101 evaluable courses there were 10 incomplete failures, 32 remissions of less than 50%, 56 remissions of more than 50% and 3 complete remissions. There was only one failure among 51 patients without previous treatment. The place of this chemotherapy in the therapeutic strategy of Hodgkin's disease is discussed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Various complexes (RnMO·BF3) of boron trifluoride with sulphoxides, aminoxides, phosphinoxides and arsinoxides have been prepared and investigated using proton, fluorine (at variable temperature) boron and phosphorus resonance. A comparison with similar adducts containing a co-ordinative O—B bond is presented.
    Notes: Les spectres de résonance magnétique nucléaire (1H, 11B, 19F et 31P) des complexes RnMO·BF3 formés par le trifluorure de bore et des sulfoxydes, aminoxydes, phosphinoxydes et arsinoxydes ont été obtenus. Les paramètres (déplacements et couplages) caractérisant ces spectres sont comparés à ceux de composés similaires renfermant également une liaison de coordination O·B.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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