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  • 1970-1974  (5)
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  • 1
    Electronic Resource
    Electronic Resource
    ECG waveform feature extraction and its application to automated prognosis (1973)
    Springer
    International journal of parallel programming 2 (1973), S. 231-247 
    Details
    ISSN: 1573-7640
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Automated correlation of ECG history for early detection of heart disease, especially among the young, has been a matter of increasing interest. However, each electrocardiogram, recorded say a few months apart, generates anywhere from 600 to 2400 digitized data, so that statistical methods cannot directly be applied. An information compression step suitable for such data is presented in this paper and a prediction procedure is developed for forecasting the waveform changes. Specifically, each ECG lead is digitized and represented by itsz-domain modes. These modes are found to exhibit continuity in time, from month to month and year to year, except in the event of major physiological changes such as after surgery, thus lending themselves ideally to statistic al prediction. To enhance discrimination of the subtle changes inP, QRS, andT complexes, the derivatives of the waves are employed for extraction of the modes. This signifies a departure from previous efforts in ECG representation. Indeed, otherwise, important changes in the waves can remain undetected through mode extraction while the human eye can perceive them rather easily from the recorded traces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00986124
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Influence of energy metabolism on the repair of X-ray damage in living cells (1972)
    Springer
    Radiation and environmental biophysics 8 (1972), S. 254-263 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Liquid-holding reactivation in the yeastS. cerevisiae after X-irradiation was observed to be inhibited in the presence of 2,4 dinitrophenol, antimycin A and KCN. However, this inhibition could be reversed by glucose. Radiation resistance and reactivation capacity of a respiratory-deficient mutant was also observed to increase by pre-irradiation incubation in glucose. It is concluded that (i) post-irradiation reactivation is an ATP-dependent process, (ii) ATP required can be supplied by the fermentative or the respiratory pathways and (iii) the intracellular energy storage system(s) can profoundly influence the cellular radiation response. Significance of these results for the radiotherapy of tumours is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01268168
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Influence of energy metabolism on the repair of X-ray damage in living cells (1973)
    Springer
    Radiation and environmental biophysics 9 (1973), S. 155-165 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Split-dose recovery (SDR), liquid-holding reactivation (LHR) and division delay reversal (DDR) in X-irradiated stationary cell populations ofSaccharomyces cerevisiae were investigated in buffer and in the presence of glucose. In buffer, all the three recovery phenomena show sigmoid type of kinetics but with some quantitative differences. DDR is completed in relatively shorter time as compared to LHR or SDR. The time needed for the completion of LHR and SDR is about the same but LHR shows a longer lag time. LHR and DDR depend upon temperature in a similar way. On adding glucose to the medium, an increase in the rate of LHR, a delay in the onset of SDR and a transient increase in the radiation sensitivity after the first irradiation are observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01215854
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Influence of energy metabolism on the repair of X-ray damage in living cells (1973)
    Springer
    Radiation and environmental biophysics 10 (1973), S. 137-142 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Effects of the glucose antimetabolite, 2-deoxy-D-glucose (2DG) on liquid-holding reactivation (LHR) in X-irradiated yeast cells were studied. It has been observed that LHR in respiratory-deficient mutants is completely inhibited at a molar concentration ratio 2DG/glucose equal to 1, whereas for the wild-type this ratio is 10. Significance of these results for a radiochemotherapy of tumors is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01191239
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Design for positive pressure respirators (1972)
    Springer
    Medical & biological engineering & computing 10 (1972), S. 253-262 
    Details
    ISSN: 1741-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Description / Table of Contents: Sommaire Cotte étude s'occupe du projet d'un respirateur à pression positive utilisant un modèle de poumon non-linéaire de premier ordre. Les non-linéarites considérées sont: la résistance de la voie aérienne non-linéaire, l'effet d'hystérésis et l'espace mort non-constant. L'analyse a été exécutée en utilisant trois différentes formes d'onde, résultent dans des périodes inspiratrices plus longues en faisant les respirateurs plus sûrs pendant le fonctionnement.
    Abstract: Zusammenfassung Die Untersuchung befasst sich mit dem Entwurf eines Sauerstoffapparats mit positivem Druck, der ein nicht-lineares Lungenmodell ersten Grades verwendet. Die in Betracht gezogenen, nicht linearen Eigenschaften sind nicht linearer Luftwegwiderstand, Wirkung der Hysterese und nicht konstanter toter Raum. Die Analyse ist mit Verwendung von drei verschiedenen Wellenformen durchgeführt worden, d.h. rechteckig, sinusförmig und abgeschrägt. Es wird gezeigt, dass die zwei letzten Wellenformen längere Einatmungszeiten ergeben, wodurch die wirklichen Sauerstoffgeräte zuverlässiger im Betrieb werden.
    Notes: Abstract This study deals with the design of a positive pressure respirator using a first order non-linear lung model. The non-linearities considered are non-linear airway resistance, effect of hysteresis and non-constant dead space. The analysis has been carried out using three different waveforms,viz., rectangular, sine and ramp. It is shown that the last two waveforms result in longer inspiratory periods making the actual respirators more reliable in operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02474115
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    Paper (German National Licenses)
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