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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 18 (1969), S. 308-310 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 44 (1966), S. 907-909 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Nuclear Instruments and Methods 16 (1962), S. 29-36 
    ISSN: 0029-554X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Nuclear Physics 30 (1962), S. 417-423 
    ISSN: 0029-5582
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 161 (1969), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 161 (1969), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 8 (1972), S. 254-263 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Liquid-holding reactivation in the yeastS. cerevisiae after X-irradiation was observed to be inhibited in the presence of 2,4 dinitrophenol, antimycin A and KCN. However, this inhibition could be reversed by glucose. Radiation resistance and reactivation capacity of a respiratory-deficient mutant was also observed to increase by pre-irradiation incubation in glucose. It is concluded that (i) post-irradiation reactivation is an ATP-dependent process, (ii) ATP required can be supplied by the fermentative or the respiratory pathways and (iii) the intracellular energy storage system(s) can profoundly influence the cellular radiation response. Significance of these results for the radiotherapy of tumours is discussed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 9 (1973), S. 155-165 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Split-dose recovery (SDR), liquid-holding reactivation (LHR) and division delay reversal (DDR) in X-irradiated stationary cell populations ofSaccharomyces cerevisiae were investigated in buffer and in the presence of glucose. In buffer, all the three recovery phenomena show sigmoid type of kinetics but with some quantitative differences. DDR is completed in relatively shorter time as compared to LHR or SDR. The time needed for the completion of LHR and SDR is about the same but LHR shows a longer lag time. LHR and DDR depend upon temperature in a similar way. On adding glucose to the medium, an increase in the rate of LHR, a delay in the onset of SDR and a transient increase in the radiation sensitivity after the first irradiation are observed.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 3 (1966), S. 44-64 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Zusammenfassung Es sollen kybernetische Untersuchungen über die Strahlenwirkung auf lebende Zellen durchgeführt werden, indem der Einfluß von Regel- und Steuervorgängen in der Zelle beim Ablauf der Strahlenreaktion quantitativ berücksichtigt wird. Dazu ist es nötig, die grundlegenden Vorgänge der Zellteilung und Vermehrung in flüssigem Medium und bei räumlicher Fixierung auf einer Agaroberfläche ebenfalls quantitativ zu behandeln. In dieser Arbeit wird die Vermehrung von Einzelzellen in homogenen und synchronisierten Populationen theoretisch untersucht. Die Berücksichtigung von Teilungsverzögerungen in der Ausgangspopulation und Schwankungen der Zykluszeit tC ergibt bei der Zellvermehrung eine Lagzeit tlag und anschließend eine genau exponentielle Vermehrung. Es werden mehrere Möglichkeiten zur experimentellen Bestimmung von Lagzeiten sowohl in flüssigen Medien wie auch auf einer Agaroberfläche angegeben, aus denen die Streuungen der Population ermittelt werden können. Durch sehr kleine Zellkonzentrationen, durch Anteile avitaler Zellen, durch Änderungen des Zustandes der Agaroberfläche und durch das Auftreten von Zellgruppen infolge einer längeren Trennzeit tT können Pseudo-Lag-zeiten entstehen, die eine verzögerte Zellteilung nur vortöuschen. Diese Möglichkeiten werden quantitativ behandelt und durch Experimente mit Hefezellen belegt.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 3 (1966), S. 140-147 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Description / Table of Contents: Summary AfterX-irradiation two different types of yeast cells can be observed. The so-calledn-cells, which cannot grow to macrocolonies, are produced by a typical “yes-no”-reaction. Their further fate (giant cells) is independent of the applied absorbed dose. The other kind of cells, the so-calledm-cells, can grow to macrocolonies. They show afterX-irradiation an induced lagtime t lag 0 . The curvature of the proliferation curve during the lagtime t lag 1 is a measure for the spread of the population of m-cells. The normal spread of yeast cells is present also afterX-irradiation, indicating that all m-cells of the population got a radiation damage of the same magnitude. This radiation effect is not a “yes-no”-reaction since the length of the induced lagtime t lag 0 is dose dependent. Diploide and haploide yeast cells show the same general behaviour. Nevertheless the sensitivity for the induced lagtime t lag 0 is within a factor of about two higher in haploide cells. This indicates differences between those strains due to reactions, which can be regulated by the cell after irradiation.
    Notes: Zusammenfassung Nach Röntgenbestrahlung vonSaccharomyces Zellen entstehen im wesentlichen zwei Zelltypen (m- undn-Zellen), deren Schicksale direkt nach Bestrahlungsende quantitativ verfolgt werden.n-Zellen werden durch eine Reaktion vomjanein-Typ erzeugt, ihr weiteres Schicksal (Aufwachsen zu Riesenzellen) ist praktisch dosisunabhängig. Diem-Zellen zeigen nach Bestrahlung eine Lagzeit, deren Länge dosisabhängig ist. Haploide Zellen verhalten sich ebenso wie diploide Zellen; für die Induktion der Lagzeit beim-Zellen sind haploide Zellen um einen Faktor zwei strahlenempfindlicher. Ein kybernetisches Modell zur Beschreibung dieser Ergebnisse wird in einer folgenden Arbeit gegeben.
    Type of Medium: Electronic Resource
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