Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    The Association Behavior of Polystyryllithium, Polyisoprenyllithium, and Polybutadienyllithium in Hydrocarbon Solvents (1970)
    s.l. : American Chemical Society
    Macromolecules 3 (1970), S. 327-332 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma60015a011
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of unlabelled and14C-labelled pindolol in uraemia (1974)
    Springer
    European journal of clinical pharmacology 7 (1974), S. 25-29 
    Details
    ISSN: 1432-1041
    Keywords: Pindolol ; uraemia ; pharmacokinetics ; β-blockade
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The elimination of pindolol in 25 patients with various degrees of renal failure has been studied after an intravenous dose of 3 mg. A linear correlation was not found between the elimination rate of pindolol and the endogenous creatinine clearance, and the half-life of the unchanged drug was independent of the severity of the renal failure. This implies greater metabolism of pindolol in anuric patients and the extrarenal elimination rate constantk mwas increased. Three patients with severe renal failure were given 3 mg14C-pindolol. They showed almost constant plasma levels of radio-activity for 6 h and then slow excretion with a half-life of 48 h, because of accumulation of metabolites in the blood. Up to 90% of the metabolites are glucuronides and sulphates which have no beta-blocking or other clinical activity. Thus, to produce beta-adrenergic blockade the same dose of indolol is required in healthy patients as in those with uraemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00614386
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Pharmacokinetic criteria for the evaluation of retard formulations (1974)
    Springer
    European journal of clinical pharmacology 7 (1974), S. 429-432 
    Details
    ISSN: 1432-1041
    Keywords: Pharmacokinetics ; retard formulations ; retard quotients ; sustained release ; half-value duration ; dibenzepin hydrochloride
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In vivo criteria are proposed for the assessment of retard formulations. If the pharmacokinetics of the retard formulation tested and of the normal preparation are known, in either plasma or urine, two retard quotients can be defined which define the sustained release. One of the quotients refers to the width (half-value duration) and the other to the height of the plasma concentration time curve of the retard form as compared to the conventional preparation. From these criteria it is possible to draw useful conclusions about thein vivo quality of a retard formulation in an early stage of development of the dosage form. As a practical example the criteria have been applied to Noveril® 240 tablets (dibenzepin hydrochloride), the retard effect of which has made it possible to reduce the frequency of administration from three times daily to once a day.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00560355
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Long-term stiffening of neoprene pads for the Poseidon missile launch system (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 16 (1972), S. 559-571 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In a previous paper1 the development of neoprene formulations and mechanical designs to meet operational requirements for the Poseidon launch tube liner pads were presented. Subsequently, it was found that early development pads aged for three months at room temperature were ∼10% stiffer than the vendor's qualification compression-deflection (C—D) test values. The increase was attributed to a combination of normal elastomer recovery and continued crosslinking due to the original low state of cure of the pads. A program was designed to study the effect of postcure time and temperature on C—D recovery, the effect of carbon black loading on the C—D recovery, and room temperature and accelerated aging at elevated temperature on these effects. Values of the molecular weight between crosslinks (M̄c) were determined experimentally to establish the state of cure. The results of these experiments are presented and discussed. Recommendations are given for reducing C—D variation by modifying carbon black loading and/or postcure conditions.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1972.070160303
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Molded neoprene liner pads for the poseidon missile launcher (1971)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 15 (1971), S. 619-640 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Neoprene formulations and mechanical designs have been developed to meet special operational requirements for the Poseidon Missile Launch System liner. The liner supports the missile in an aligned position, provides shock mitigation, reacts properly with the missile during launch, and damps vibrations. Operational requirements include static and dynamic compressive stiffness, damping, and water drainability. A mechanical design was evolved that utilized notched, prebuckled struts as supporting members. Compression-deflection characteristics were modified by simultaneous changes in geometrical design and polymer formulation. A study of the effects of variations in polymer compounding and mechanical design on the compressive stiffness, rate sensitivity of the compression-deflection characteristics, and vibrational damping is described. Mold release agents and their role in successful production are discussed.
    Additional Material: 23 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1971.070150310
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Studies on akroflex CD antioxidant loss from neoprene rubber. I. The determination of antioxidant content and the loss mechanism during aging (1974)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 18 (1974), S. 3543-3553 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: An analytical procedure for determining the antioxidant (i.e., Akroflex CD) content in neoprene rubber has been developed. The method is based on the infrared absorption analyses of chloroform extractables from the cured rubber at 1600 cm-1 and 1300 cm-1. Good agreement is found between these two independent sets of measurements. In an attempt to elucidate the antioxidant loss mechanism found with neoprene, thermal aging studies were carried out over the temperature range of 80°-200°C. Using the infrared analytical procedure, antioxidant loss rates at the different temperatures were established. The activation energy value (5.1 kcal/mole) for the loss rate as well as other aging data suggest that the antioxidant is lost by a diffusion mechanism.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1974.070181205
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    An electrochemical route to phenol-formaldehyde precursors (1974)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 12 (1974), S. 1193-1202 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: With the aid of VPC and NMR, the electroinitiated polymerization of phenol or p-tert-butyl phenol with formaldehyde in the presence of basic electrolytes has been investigated over a range of current densities. Results from an electroinitiation study were contrasted with base-catalyzed thermal polymerizations and, except for yield, found to be essentially invariant. GPC of the electroinitiated and thermally polymerized resins indicates similar results with low molecular weight species of relatively narrow molecular weight distribution being the principal products. An electroinitiation mechanism, in agreement with the mechanism for base-catalyzed thermal polymerization is proposed to describe these experimental results.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1974.170120606
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...