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  • 1
    Electronic Resource
    Electronic Resource
    The effects of hyperthyroidism on the fine structure of the zona fasciculata of the rat adrenal cortexThis research supported by NIH grants DHEW 5T01 GM 00459 and 2R01 NS 00690. (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 174 (1972), S. 451-467 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Chronic hyperthyroidism was induced in radiothyroidectomized and surgically thyroidectomized adult male rats by feeding a diet of 0.3-0.4% desiccated thyroid for four to ten week periods. Short term hyperthyroidism was induced in intact rats by the intraperitoneal injection of 250 μg/day of sodium levothyroxine for ten days. Adrenal glands were fixed by perfusion with 3% phosphate buffered glutaraldehyde and post-fixed in 1% osmium tetroxide. The zona fasciculata of the adrenal glands from experimental and control animals was examined in the electron microscope. Drastic mitochondrial alterations characterized the zona fasciculata of hyperthyroid rats. Initially, mitochondria became more nearly round and contained increased numbers of paracrystalline tubular inclusions of the type described by Kjaerheim ('67) and Wheatley ('68). In more altered states many mitochondria were filled with clusters of parallel tubular cristae of varying complexity which at times enveloped islands of mitochondrial matrix and fingers of cytoplasm which projected into the mitochondrion. Aggregations of numerous mitochondria occupied much of the cytoplasm of highly altered cells. Modifications of this nature have not been described following ACTH stimulation of the adrenal cortex. This raises the distinct possibility that thyroid effects on the adrenal cortex are not entirely ACTH mediated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091740405
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  • 2
    Electronic Resource
    Electronic Resource
    Bond rupture during ozone cracking of torsional loaded styrene-butadiene (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 16 (1972), S. 1377-1386 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The molecular bond rupture rate during ozone attack of torsionally loaded rubber was determined from electron paramagnetic resonance (EPR) measurements. The rupture rate was successfully correlated by a Griffith-type energy balance to the strain-energy release rate in the samples. These observations substantiate the results from a similar study on tensile loading previously reported. In both cases there is a one-to-one correspondence between the rate of bond rupture (or crack growth) and the rate of energy release from the strain field and external work. A fracture energy, γn, of approximately 5×10-12 (±20%) ergs per free radical formed during the cracking was experimentally determined.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1972.070160606
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    Paper (German National Licenses)
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