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  • 1970-1974  (4)
  • 1
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A girl with severe combined immunodeficiency and pronounced malnutrition from chronic diarrhoea is presented. Immunological reconstitution was attempted by transplantation of bone marrow cells from the HL-A hemiallogeneic father. An initial transplant failed to induce a permanent take of the graft, whereas a second transplant with an increased cell dose ensured a take, which was followed by reconstitution of cell-mediated immune functions. Fractionation of the transplanted bone marrow cells apparently led to a delay in development of graft-versus-host symptoms. Germ-free isolation and extensive bacterial decontamination markedly reduced the microbial flora and was highly protective against contaminating microorganisms but failed to eradicate completely one strain of Escherichia coli that had invaded the child before institution of this regimen. During a moderate, delayed graft-versus-host reaction this strain caused widespread severe infection, to which the child succumbed 10 weeks after the second transplantation. This child presented some additional features, the most conspicuous being a deficiency of erythrocyte adenosine deaminase.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 2 (1973), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Determination of the Y chromatin body should rank among the battery of techniques used to assess the presence of grafted bone marrow cells in cases of male donor and female recipient. The method permits early determination of a take, and probably some measurement of its magnitude. This might provide correlation between level of grafted cells and occurrence of various parameters indicating an immune reconstitution and/or an eventual GVH reaction. The technique may be a highly sensitive marker for chimaerism in cases of histocompatibility between donor and recipient of different sexes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 43 (1971), S. 1471-1474 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Mineralium deposita 8 (1973), S. 64-72 
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Abstract δ34S-values are given for 67 sulfide and 16 barite specimens from the Pb-Zn-deposit Grund (Harz mountains, W-Germany). In the central part of the deposit the sulfide δ's of the first major mineralization (phase II) range from: ZnS +4 to +6 and PbS +2 to +4‰. The sulfides of the second major mineralization (phase III) are depleted in 34S and range from: ZnS +2 to +4, PbS −1,4 to 3‰. The sulfides at the western end of the vein system are heavier; the phase II minerals ranging from: ZnS +6 to 10 and PbS +4 to 7‰. The mean δ-difference between co-existing ZnS and PbS in phase II is ≈ 1,8‰, in phase III ≈ 3‰. This indicates lowering of temperature of formation for the phase III ore. Four models have been set up in order to explain the observed δ-variation. Barites with rather uniform δ's from +11 to +14,5‰ are probably affected by descendent solutions from overlying sulfate sediments of Permian age.
    Notes: Zusammenfassung Die S-Isotopenverteilung wurde an 67 Sulfid- und 17 Barytproben aus der Blei-Zink-Erzlagerstätte Grund untersucht. Die δ34S-Werte der Zinkblende der Mineralisationsphase II liegen im Westfeld-Erzmittel I und in den östlich anschließenden Erzmitteln zwischen +4 und +6‰, in dem am weitesten westlich liegenden Westfeld-Erzmittel II zwischen +6 und +10‰. Die Werte für Bleiglanz der Mineralisationsphase II sind +2 bis +4 bzw. +4 bis +7‰. Die Sulfide der Mineralisationsphase III haben allgemein niedrigere δ-Werte. Koexistierende Sulfide zeigen eine deutliche Fraktionierung, wobei stets δZnS 〉 δPbS ist; die Differenz beträgt in der Mineralisationsphase II im Mittel ≈ 1,8‰, in der Phase III ≈ 3‰. Dies deutet auf niedrigere Bildungstemperatur der Minerale der Phase III hin. Zur genetischen Deutung der beobachteten δ-Abnahme beim Übergang zur Mineralisationsphase II werden vier Modelle diskutiert. Baryte zeigen innerhalb der Lagerstätte recht einheitliche δ34S-Werte zwischen +11 und +14,5%. Diese Einheitlichkeit wird durch den Einfluß deszendenter Zechstein-Lösungen erklärt.
    Type of Medium: Electronic Resource
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