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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 17 (1973), S. 50-62 
    ISSN: 1432-1106
    Keywords: Cerebellum ; Barbiturates ; Unitary activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In precollicular decerebrate cats, limb nerves have been stimulated and field potentials and unitary activity recorded from the cerebellar cortex. Doses of pentothal up to 8 mg/kg affect neither the activity evoked in the fast mossy fibre pathways, nor the size of the postsynaptic potentials in granule cells, but the axon discharge in these latter cells is clearly affected. With 4–8 mg/kg the axon discharge of granule cells is abolished and as a consequence Purkinje cells do not respond to the peripheral stimulation via the mossy fibres. In contrast the activity evoked through the climbing fibres is enhanced. This effect takes place at precerebellar level. Both the effects on the mossy fibre and climbing fibre pathways show a recovery in 15–60 min depending on the dose.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 314 (1970), S. 68-85 
    ISSN: 1432-2013
    Keywords: Cerebellärer Cortex ; Faserentladungen ; Evoked Potentials ; Cerebellar Cortex ; Fiber Responses ; Evoked Potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary To investigate the relationship between the surface evoked potentials of the superficial radial nerve and the splanchnic nerve, and the fiber evoked responses of the cerebellum of the cat was the purpose of the present study. The discharges of the mossy fibers, climbing fibers and Purkinje cell axons were identified and their relationship with the surface-potentials established. The mossy fibers fire with train of spikes in different groups, which probably correspond to impulses transmitted through fibers of different conduction velocities and synchronously with the first positivity of the evoked potential. Climbing fibers respond synchronously with the development of the sharp negative deflection of the evoked potentials and were, for the first time, identified. Finally, the Purkinje cell axons exhibited the same firing pattern as the Purkinje cells. Cutaneous and visceral afferents use not only common elements of the cerebellar cortex but also common pathways, in spite of measurable differences between both afferents.
    Notes: Zusammenfassung Der Zweck der vorliegenden Arbeit war die Beschreibung der Beziehung zwischen den Oberflächen-Evoked Potentials, ausgelöst durch Reizung des N. radialis superficialis und des N. splanchnicus und den evozierten Faserentladungen am Kleinhirn der Katze. Die Entladungen der Moosfasern, Kletterfasern und Axone der Purkinje-Zelle wurden identifiziert und ihre Beziehung zu den Oberflächenpotentialen festgestellt. Die Moosfasern feuern mit Spikesalven und in verschiedenen Gruppen. Diese entsprechen wahrscheinlich Impulsen, die von Fasern mit verschiedener Leitungsgeschwindigkeit fortgeleitet werden und die synchron mit der ersten Positivität der Evoked Potentials sind. Die Kletterfasern stehen in zeitlicher Beziehung zu der Entwicklung der scharfen negativen Ablenkung des EPs und werden zum ersten Male identifiziert. Schließlich weisen die Axone der Purkinje-Zelle dieselben Entladungsmuster auf wie die Purkinje-Zelle selbst. Cutane und viscerale Afferenzen benutzen nicht nur gemeinsame Elemente des cerebellären Cortex, sondern wahrscheinlich auch gemeinsame Leitungswege, obwohl es quantitative Differenzen zwischen beiden Afferenzen gibt.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2013
    Keywords: Cerebellärer Cortex ; Instrumentelle Konditionierung ; Licht-Dunkelheit-Diskrimination ; Cerebellar Cortex ; Instrumental Conditioning ; Light-Dark-Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Eighteen cats were used as subjects in a study which investigated the effects of bilateral cortical cerebellar hemispheric ablations upon light-dark discrimination learning. From the operated control group (8 animals), 5 were tested two weeks and 3 three weeks postoperatively. From the experimental group (10 animals) 4 were tested two weeks and 6 three weeks postoperatively. The discrimination task consisted of an instrumentally conditioned bar-pressing response. The results showed that almost during the entire 23-day learning period, the experimental cats performed more poorly on the discrimination task than their controls. It is hypothesized that the difference between the two groups of animals derives from the disturbance (caused by the ablation) of the connections between the cerebellum and other structures involved in the habituation process.
    Notes: Zusammenfassung 18 Katzen wurden als Versuchstiere in einem Experiment benutzt, welches den Einfluß der bilateralen Entfernung des corticalen Teils der cerebellären Hemisphären auf das Erlernen einer Licht-Dunkelheit-Diskrimination untersuchte. Von der operierten Kontrollgruppe (8 Tiere) wurden 5 zwei Wochen und 3 drei Wochen nach der Operation getestet. Von der experimentellen Gruppe (10 Tiere) wurden 4 zwei Wochen und 6 drei Wochen nach der Operation getestet. Die Diskriminationsaufgabe bestand aus Hebeldrücken nach der Skinner-Methode. Die Ergebnisse zeigten, daß die experimentellen Tiere fast während der ganzen Lernperiode (23 Tage) weniger Diskriminationsvermögen aufweisen als die Kontrolltiere. Es wurde vermutet, daß dieser Unterschied zwischen den experimentellen Tieren und den Kontrolltieren darauf beruht, daß die Entfernung eines Teils des cerebellären Cortex die Verbindungen zu Strukturen, die bei dem Habituationsprozeß eine Rolle spielen, stört.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 320 (1970), S. 97-110 
    ISSN: 1432-2013
    Keywords: Cerebellar Cortex ; Evoked Potentials ; Visceral Afferents ; Kleinhinrinde ; Evoked Potentials ; Viscerale Afferenzen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Evoked Potentials nach Reizung des N. radialis superficialis und N. splanchnicus wurden an der Kleinhirnrinde untersucht und ihre Verteilung mappiert. Es wurde festgestellt, daß die Potentiale der beiden Afferenzen sich stark voneinander unterscheiden. Die verschiedene Form weist darauf hin, daß beide Afferenzen von der Kleinhirnrinde unterschiedlich verarbeitet werden. Durch Interaktions-, Frequenzversuche und Input-Output-Kurven wurden diese Differenzen analysiert.
    Notes: Summary After stimulation of the superficial radial nerve and the splanchnic nerve, evoked potentials were recorded on the surface of the cerebellum and their distribution mapped. It was shown, that the potentials of both afferents were quite different from each other. The differences in shape indicate that both afferents are differentially organized by the cerebellar cortex. This conclusion was reached through interaction experiments, frequency studies, and input-output-relation.
    Type of Medium: Electronic Resource
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