ISSN:
1573-8221
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary A study was made of the effect on diuresis of spasmodic attacks, provoked by various methods. To induce these, substances differing by their chemical nature and pharmacological action were used (camphor, Corazol, Pyramidon), along with electric current. As established, camphor and Corazol lead to a strong prolonged spasmodic attack, since no habituation to these preparations develops. Although Pyramidon is capable of inducing a spasmodic attack of adequate length and strength, it is not very useful in chronic experiments, since habituation to this drug is rather rapid. Spasmodic attacks provoked by electric current passed through the animal's head are somewhat less strong and prolonged in comparison with the convulsion caused by pharmacological agents. Thus, the character of diuretic changes occurring in spasmodic attack does not depend on the agent provoking the convulsions; inhibition of diuresis was observed in all of the experiments. The duration and the depth of this inhibition depended on the strength of convulsive attack and the initial diuresis background.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00783504
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