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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 43 (1978), S. 1430-1434 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 35 (1975), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In a solution culture experiment with 4-week-old barley plants (variety Villa) the influence of NaCl salinization and of KCl additions on the uptake and turnover of labelled N (15NH415NO3) was studied. Labelled N was applied for 24 h at the end of the growth period.Salinization impaired growth and uptake of labelled N. The incorporation of labelled N into the protein fraction, however, was improved by NaCl salinization. Additions of KCl to the nutrient solution diminished the negative effect of NaCl salinization on growth. At both NaCl salinization levels (60 and 120 mM) K additions favoured the uptake of labelled N and particularly its incorporation into the protein fraction.It is suggested that the negative influence of the NaCl stress is not primarily due to an impaired protein synthesis, but is possibly caused by a deterimental effect of Na on other metabolic processes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 279 (1979), S. 104-105 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two ionic fluxes, akin to those initiating and transducing nerve impulses, may be essential regulators of animal cell proliferation. This idea emerged at a recent conference* where many findings pointed to increased Na+ influx being an early, perhaps the initial, mitogenic signal, and to ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Cell isolation procedures and plating methods (which use arginine-free medium to select for arginine-synthesising hepatocytes6) are given in Fig. 1 (legend). About 10% of the cells in 5-7 g of normal liver are recovered for plating. Over 95 % of these cells are viable (measured by trypan-blue ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 105 (1943), S. 89-97 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Zusammenfassung Der übergang vom normal-zum supraleitenden Zustand erfolgt, zumindest dann, wenn er im Magnetfeld stattfindet, über einen Zwischen-(Mikro-)zustand, der durch 0 〈Μ 〈 1 gekennzeichnet ist (voller SupraleitzustandΜ=0). Man hat angenommen, da\ der Supraleiter in diesem Zustand aus mikroskopischen Bereichen (schmale Zylinder in Feldrichtung) bestehe, die voll sl. und durch nl. ZwischenrÄume getrennt sind. Auf Grund dieser Vorstellung lÄ\t sich zunÄchst das Verhalten sl. Hohlkörper im Magnetfeld, das auffallende Abweichungen gegenüber dem Verhalten massiver Körper aufweist, völlig verstÄndlich machen. Gewisse Hysteresiserscheinungen, die beim übergangN—S auftreten, sprechen dafür, da\ der Mikrozustand die notwendige Begleiterscheinung einer sich aus Keimen entwickelnden Umwandlung sei. Diese dynamische Auffassung der Entstehung des Zwischenzustarrdes führt zu einer ganz trivialen ErklÄrung des Mei\ner-Effektes (VerdrÄngung eines vor dem Abkühlen eingeschalteten Magnetfeldes aus dem Sl. beim übergang): in der wachsenden OberflÄche wird nach dem Durchflutungsgesetz ein Abschirmstrom induziert. Es zeigt sich schlie\lich, da\ der übergang vom normal- zum supraleitenden Zustand am ehesten zu. verstehen ist, wenn man annimmt, da\ der metallische Leiter ein Gemenge zweier Atomgattungen ist, von denen nur die eine als TrÄger des Leitungsvorganges in Betracht kommt, und da\ die UmwandlungN—S in der Bildung einer überstruktur der beiden Atomgattungen, die sich nur durch den Aufbau ihrer Elektronenhüllen unterscheiden (dia- und paramagnetisch?) bestehe. Es wird zum Schlu\ darauf hingewiesen, da\ auch bei gewöhnlichen überstrukturen (z. B. bei CuAu) metastabile MikrozustÄnde auftreten, die zu Hysteresiserscheinungen Anla\ geben.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 121 (1943), S. 488-494 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 122 (1944), S. 706-713 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Schickt man durch einen tordierten Eisen- oder Nickeldraht einen Wechselstrom beliebiger Frequenz, während der Draht gleichzeitig einem allmählich anwachsenden magnetischen Längsfeld ausgesetzt wird, so erfolgt der Anstieg der longitudinalen Magnetisierung in großen Sprüngen, die mit der Wechselfrequenz synchron sind. Der Effekt läßt sich in Analogie mit dem Sixtus-Tonks-Effekt durch die Annahme erklären, daß die zirkuläre Magnetisierung infolge der Torsionsspannung die Keime für die longitudinale Magnetisierung liefert und daß ein großer Sprung der Magnetisierung jeweils die gesamten Keime verbraucht, so daß die Sprünge in der Frequenz der keimerzeugenden zirkulären Magnetisierung erfolgen müssen.
    Type of Medium: Electronic Resource
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  • 8
    facet.materialart.
    Unknown
    Manchester : Periodicals Archive Online (PAO)
    Journal of Semitic studies. 23 (1978) 127 
    ISSN: 0022-4480
    Topics: Linguistics and Literary Studies , Ethnic Sciences
    Notes: REVIEWS
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  • 9
    facet.materialart.
    Unknown
    Manchester : Periodicals Archive Online (PAO)
    Journal of Semitic studies. 23 (1978) 127 
    ISSN: 0022-4480
    Topics: Linguistics and Literary Studies , Ethnic Sciences
    Notes: REVIEWS
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 16 (1979), S. 255-262 
    ISSN: 1432-1041
    Keywords: spironolactone ; canrenone ; fluorimetry ; high performance liquid chromatography ; linear kinetics ; saturation kinetics ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In Study I 20 normal volunteers received a single oral dose of spironolactone 100 mg. In Study II a further 20 normal volunteers were given first spironolactone 100 mg b.i.d. and subsequently spironolactone 100 mg once a day for a further 4 days. In Study III 5 normal subjects were given a single dose of spironolactone 500 mg. The concentration of canrenone in serum was determined both by fluorimetry and HPLC for 0–48 h in Study I, 120–168 h in Study II and 0–36 h in Study III. The total AUCs after the single 100 mg dose did not differ from the AUCs within the dosing interval during steady state. The half-lives of the terminal log-linear phases were almost identical (14.99±0.80 h and 15.69±0,80 h) when determined by fluorimetry, and were sligthly, but significantly (p〈0.01), longer when determined by HPLC — 20.14±1.62 and 18.71±1.04. The mean ratio of the specific AUC determined by HPLC and the fluorimetrically determined AUC was 0.3 after the single 100 mg dose. It did not differ from the corresponding value during steady state (0.34). In contrast, the ratio after the single 500 mg dose was approximately 50% higher. Fluorimetrically determined AUCs after 100 and 500 mg doses did not show dose-proportionality in contrast to the HPLC-determined AUCs. It was concluded that Canrenone contributes much less to the conventional fluorimetric determination than was previously assumed. It may not provide more than 1/10 and 1/4 of the antimineralocorticoid activity of spironolactone after single dose and multiple doses, respectively. Whereas linear kinetics apply after single and multiple 100 mg doses of spironolactone, after 500 mg saturation kinetics must be assumed with respect to metabolism. Thus, in bioavailability studies high doses of spironolactone should be avoided. For such studies the fluorimetric assay seems to be the appropriate bioanalytical method in spite of its lower specificity.
    Type of Medium: Electronic Resource
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