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  • 1
    Electronic Resource
    Electronic Resource
    Acute leukemia with chromosome translocation (4; 11): 7 new patients and analysis of 71 cases (1987)
    Springer
    Annals of hematology 54 (1987), S. 325-335 
    Details
    ISSN: 1432-0584
    Keywords: Acute leukemia ; (4; 11) chromosome translocation ; Early B-precursor cell origin ; Mixed lineage leukemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Clinical and laboratory features of seven patients with acute leukemia associated with the (4; 11) chromosome translocation are presented. Leukemic blasts of these patients showed lymphoid morphology in 6 (although 1 was treated for monoblastic leukemia 3 years earlier) and monocytoid morphology in 1, were positive for TdT and HD 37 (CD 19) in 6 patients, whereas weak expression of CALLA was seen in only 1 patient and T-lineage-associated antigens in none. Leukemic blasts from four patients showed the simultaneous expression of B-lymphoid and myeloid antigens, suggesting leukemogenesis in a very early multipotent progenitor cell. In 2 patients an isochromosome of the long arm of No. 7 chromosome was found in the leukemic karyotypes in addition to t (4; 11) (q21; q23); in one instance present at diagnosis, in the other one occurring at relapse. In one other patient leukemia karyotype also demonstrated trisomy 8. Leukemic cells of three patients were investigated by molecular genetics and demonstrated immunoglobulin gene rearrangements for the Ig heavy chain sequences but not for the light chain constant regions and T cell receptor sequences. All patients were treated by intensive chemotherapy. Four of the 7 patients are in continuous complete remission. The longest event-free survival time (over 2 1/2 years) was seen in one patient who had also DOWN-syndrome. Including these 7 patients a clinical analysis of 71 patients with t (4; 11) acute leukemia was made, emphasizing the following characteristics at diagnosis: female sex (62%), age under 2 years (49%), leukocyte count over 100×109/1 (61%), splenomegaly (80%), CNS-disease (11%). Survival of over 2 years was reported in less than 15% of the patients. It remains to be seen if risk-adapted treatment can alter the course of this early B-precursor acute leukemia with hitherto very bad prognosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00626012
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  • 2
    Electronic Resource
    Electronic Resource
    Tetra- und Pentacarbonyl-Derivate der Metalle Chrom, Molybdän und Wolfram mit sauerstoff- und schwefelverbrückten Distibanen sowie mit Chlorodiphenylstiban als KomplexligandenProfessor Otto J. Scherer zum 60. Geburtstage gewidmet (1993)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 619 (1993), S. 1991-1997 
    Details
    ISSN: 0044-2313
    Keywords: Pentacarbonyl(diorganostibine)chromium, -molybdenum, -tungsten complexes ; Tetracarbonyl(diorganostibine)chromium and -molybdenum complexes ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Tetra- and Pentacarbonyl Compounds of Chromium, Molybdenum and Tungsten with Oxygen- and Sulfurbridged Distibines and with Chlorodiphenylstibine as Complex LigandsThe penta- and tetracarbonyl complexes of chromium, molybdenum and tungsten with the stibines Ph2SbCl and (Ph2Sb)2X (X = O and S) are obtained by photochemical reaction of the hexacarbonyls in thf and by thermic ligand substitution of (η4-C7H8)M(CO)4 (M = Cr, Mo) with stibines.In the case of (Ph2Sb)2X monodentate or bidentate coordination is possible.
    Notes: Die Synthese von Penta- und Tetracarbonylen der Metalle der 6. Nebengruppe mit Antimonliganden des Typs Ph2SbCl und (Ph2Sb)2X (X = O und S) erfolgt durch photochemische Umsetzung der Metallhexacarbonyle in THF bzw. durch thermische Ligandsubstitution aus (η4-C7H8)M(CO)4 (M = Cr, Mo) mit den Antimonliganden.Bei Verwendung der Chelatstibane (Ph2Sb)2X läßt sich sowohl eine monodentate als auch eine bidentate Koordination verwirklichen.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19936191206
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  • 3
    Electronic Resource
    Electronic Resource
    Eisen- und Mangankomplexe mit sauerstoff-, schwefel- und methylen-verbrückten Distibanen und mit Chlorodiphenylstiban als Liganden (1993)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 619 (1993), S. 2061-2065 
    Details
    ISSN: 0044-2313
    Keywords: Dicarbonylbis(triphenylphosphite)(stibine)iron complexes ; Bis[dicarbonylbis(triphenylphosphite)iron](stibine) complexes ; Dicarbonyl(η5-methylcyclopentadienyl)(stibine)manganese complexes ; Bis[dicarbonyl(η5-methylcyclopentadienyl)manganese](stibine) complexes ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Complexes of Iron and Manganese with Oxygen-, Sulfur-, and Methylene-bridged Distibines and with Chlorodiphenylstibine as LigandsThe photochemical reaction of CO3Fe[P(OPh)3]2 and of MeCpMn(CO)3 with the stibines Ph2SbCl and (Ph2Sb)2X (X = O, S and CH2) yields mononuclear complexes (CO)2[P(OPh)3]2FeL and °Cp(CO)2MnL (L = Ph2SbCl, (Ph2Sb)2X) and the stibine bridged binuclear complexes °CO)2[P(OPh)3]2Fe{(Ph2Sb)2X}Fe(CO)2[P(OPh)3]2 and °Cp(CO)2Mn{(Ph2Sb)2X}Mn(CO)2MeCp.
    Notes: Durch photochemische Umsetzung von (CO)3Fe[P(OPh)3]2 und von MeCpMn(CO)3 mit Anti-monliganden des Typs Ph2SbCl und (Ph2Sb)2X (X = O, S und CH2) können Einkernverbindungen (CO)2[P(OPh)3]2FeL und MeCp(CO)2MnL (L = Ph2SbCl, (Ph2Sb)2X sowie die über Distibanliganden verbrückten Zweikernverbindungen (CO)2[P(OPh)3]2Fe{(Ph2Sb)2X}Fe(CO)2[P(OPh)3]2 und MeCp(CO)2Mn{(Ph2Sb)2X}Mn(CO)2MeCp synthetisiert werden.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19936191215
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