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  • Chemistry  (23)
  • 25.30.Dh  (3)
  • ARDS  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Octreotide treatment in patients with necrotizing pancreatitis and pulmonary failure (1996)
    Springer
    Intensive care medicine 22 (1996), S. 909-915 
    Details
    ISSN: 1432-1238
    Schlagwort(e): Key words Acute pancreatitis ; Necrotizing pancreatitis ; Octreotide ; Treatment ; Systemic complications ; SIRS ; ARDS ; Circulatory shock
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract   Objective: To determine the efficiency of intravenous infusion of octreotide in the treatment of patients with severe pancreatitis and pulmonary failure. Design: Prospective, case–control study. Setting: Intensive care unit of a university hospital. Patients: Treatment group: 39 patients with necrotizing pancreatitis were selected for the study. In all, pulmonary failure developed under conservative treatment and surgical intervention had been necessary because of local (abscess, necrosis) or systemic (systemic inflammatory response syndrome) complications. The outcome was prospectively followed up until death or discharge from the hospital. Control group: 54 case–control matched patients with acute necrotizing pancreatitis and pulmonary failure, who had not been treated with octreotide. Intervention: Each patient in the treatment group received 100 μg intravenous octreotide three times daily for 10 days, in addition to the standard intensive care therapy. Results: The groups (octreotide group, control group) were highly comparable with regard to age (mean age: 54, 51 years), sex, severity of illness (Acute Physiology and Chronic Health Evaluation II score: 27, 27), etiology of pancreatitis, and pretreatment at the time of admission to the intensive care unit. There was no difference in the development of renal, hepatic, gastrointestinal, hemostatic, neurologic, or local complications. But the frequency of the adult respiratory distress syndrome (18 vs 40%; p〈0.05) and circulatory shock (51 vs 87%; p〈0.05) was significantly lower in the treatment group. Furthermore, mortality was 26% (10 of 39 patients) in the octreotide group and 61% (33 of 54 patients) in the control group (p〈0.01). Conclusion: The results of our case–control study showed a beneficial effect of octreotide in patients with severe necrotizing pancreatitis and pulmonary failure. Based on these data, a prospective, double-blind, placebo-controlled study should be performed to evaluate these results.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s001340050186
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  • 2
    Digitale Medien
    Digitale Medien
    Octreotide treatment in patients with necrotizing pancreatitis and pulmonary failure (1996)
    Springer
    Intensive care medicine 22 (1996), S. 909-915 
    Details
    ISSN: 1432-1238
    Schlagwort(e): Acute pancreatitis ; Necrotizing pancreatitis ; Octreotide ; Treatment ; Systemic complications ; SIRS ; ARDS ; Circulatory shock
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Objective To determine the efficiency of intravenous infusion of octreotide in the treatment of patients with severe pancreatitis and pulmonary failure. Design Prospective, case-control study. Setting Intensive care unit of a university hospital. Patients Treatment group: 39 patients with necrotizing pancreatitis were selected for the study. In all, pulmonary failure developed under conservative treatment and surgical intervention had been necessary because of local (abscess, necrosis) or systemic (systemic inflammatory response syndrome) complications. The outcome was prospectively followed up until death or discharge from the hospital. Control group: 54 case-control matched patients with acute necrotizing pancreatitis and pulmonary failure, who had not been treated with octreotide. Intervention Each patient in the treatment group received 100 μg intravenous octreotide three times daily for 10 days, in addition to the standard intensive care therapy. Results The groups (octreotide group, control group) were highly comparable with regard to age (mean age: 54, 51 years), sex, severity of illness (Acute Physiology and Chronic Health Evaluation II score: 27, 27), etiology of pancreatitis, and pretreatment at the time of admission to the intensive care unit. There was no difference in the development of renal, hepatic, gastrointestinal, hemostatic, neurologic, or local complications. But the frequency of the adult respiratory distress syndrome (18 vs 40%;p〈0.05) and circulatory shock (51 vs 87%;p〈0.05) was significantly lower in the treatment group. Furthermore, mortality was 26% (10 of 39 patients) in the octreotide group and 61% (33 of 54 patients) in the control group (p〈0.01). Conclusion The results of our case-control study showed a beneficial effect of octreotide in patients with severe necrotizing pancreatitis and pulmonary failure. Based on these data, a prospective, double-blind, placebo-controlled study should be performed to evaluate these results.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02044115
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  • 3
    Digitale Medien
    Digitale Medien
    Electroexcitation of magnetic dipole and other modes in46Ti and48Ti (1990)
    Springer
    The European physical journal 336 (1990), S. 159-178 
    Details
    ISSN: 1434-601X
    Schlagwort(e): 21.60.-n ; 25.30.Dh ; 27.40.+z
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract With high-resolution inelastic electron scattering measurements on46Ti and48Ti the excitation mechanism of the transition into low lying Jπ=1+ states is investigated. The experimental evidence of considerable contribution of the orbital part of theM1 operator to the total transition strength is given by a model dependent analysis of form factors. The possibility of physical relationship to low lying Jπ=1+ states in the rare earth nuclei is discussed in various models. MoreoverE2 form factors and good candidates forM3 form factors are presented.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01290617
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  • 4
    Digitale Medien
    Digitale Medien
    No evidence for medium effects in the12C(e, e'p)11Bg.s. reaction (1995)
    Springer
    The European physical journal 351 (1995), S. 353-354 
    Details
    ISSN: 1434-601X
    Schlagwort(e): 21.10.Pc ; 25.30.Dh ; 24.50.+g ; 27.20.+n
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract The12C(e, e'p)11B g.s reaction has been measured in parallel and anti-parallel kinematics over ap m range of −120〈p m〈120 MeV/c at a centralT p of 90 MeV. In contrast to previous measurements at NIKHEF, both kinematics can be described without enhancement of the transverse form factor of the bound proton (η=0.98(5)). The spectroscopic factor for this transition as determined with the new Mainz data (S α =1.54(5)) is 22% smaller than the NIKHEF value.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01291135
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  • 5
    Digitale Medien
    Digitale Medien
    Line shape and excitation strength of the first excited state in9Be (1987)
    Springer
    The European physical journal 326 (1987), S. 447-454 
    Details
    ISSN: 1434-601X
    Schlagwort(e): 21.60.CS ; 25.30.Dh ; 27.20.+n
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract The line shape and the excitation strength of the very weak first excited J π =1/2+ state at Ex=1.684 MeV in Zeitschrift für Physik Zeitschrift für Physik9Be has been investigated with high-resolution inelastic electron scattering at E0=45 and 49 MeV and scattering angles θ=105°, 117°, 129° and 165°, and with high-resolution inelastic proton scattering at E0=13MeV and θ=15° and 18°. Due to lying just above the neutron threshold the level has a strongly asymmetric line shape which in both experiments can be described consistently with a Breit-Wigner expression modified on the low energy side by the threshold behaviour of the cross section. The resonance energy is ER=1.684 ± 0.007 MeV and the width T=217± 10 keV in thec.m. system. A single particle potential model calculation reproduces the line shape and the resonance parameters fairly well. In addition, the inelastic electron scattering form factor has been measured. In the range of momentum transfersq =0.24-0.46 fm−1 it is dominated by a 0p3/2→ 1s1/2 particle-hole transition. The transition is mainly longitudinal and of isoscalar nature with a strength of B (E1)↑ =0.027 + 0.002 e2 fm2, but a small M2 contribution ofB(M2)↑=8.8 ±1.5 μ N 2 fm2 has also been detected.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01289549
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  • 6
    Digitale Medien
    Digitale Medien
    Organische Elektronenleiter und Vorstufen. V.IV. Mitt.: RICHTER, A. M.; FANGHÄNEL E.: Sulfur Lett. 3 (1985) 25. Synthese von Poly(organylthio-acetylenen) (1987)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 329 (1987), S. 811-816 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Organic Electron Conductors and Precursors. V. Synthesis of Poly (organylthio-acetylenes)Poly(bis-organylthio-acetylenes) 2 and poly(mono-organylthio-acetylenes) 3 have been synthesized by complex catalyzed polymerization of the corresponding acetylenes (4 resp. 5). Yields and properties of the polymers 2, 3 depend on reaction conditions, the catalyst and the nature of the acetylenes. Relations between these influence factors are discussed.
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19873290509
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  • 7
    Digitale Medien
    Digitale Medien
    Heterocyclisch substitutierte Arendiazoniumsalze mit erweiterter spektraler Empfindlichkeit - Teil I: Monomethine und AzamethineHerrn Professor Dr. E. Schmitz zum 60. Geburtstag gewidmet (1988)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 330 (1988), S. 590-606 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Heterocyclic Substituted Arendiazonium Salts with a Long-wave-length Range of Sensitivity  -  Part I: Monomethins and AzamethinsTwo new types of arendiazonium salts have been synthesized. In these compounds a heterocycliden ring is bridged through a methine group (8a-o) or a nitrogen (11a-c) with the 4-position of a benzene diazonium group.Both types show sensitivity towards normal day-light, their long wave-length absorption band vary from 430 nm up to 590 nm, depending on the donor strength of the heterocycliden ring and the nature of the bridging group.The thermostability, the quantum yields of photochemical dediazonation and the coupling behaviour of the diazonium salts are investigated, in order to evaluate their potential applicability in a commercial diazotype system.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19883300413
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  • 8
    Digitale Medien
    Digitale Medien
    Heterocyclisch substituierte Arendiazoniumsalze mit erweiterter spektraler Empfindlichkeit. II. 4-(1-Heterocycliden-2,3-diaza-prop-2-en-3-yl)-benzendia-zoniumtetrafluoroborateHerrn Prof. Schulz zum 60. Geburtstag gewidmet (1990)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 332 (1990), S. 43-54 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Heterocyclic Substituted Arenediazonium Salts with a Long-wave-length Range of Sensitivity. II. 4-(1-Heterocycliden-2,3-diaza-prop-2-en-3-yl)-arenediazonium tetrafluoroboratesThe title compounds (3) are obtained by reaction of aromatic bis-diazonium salts with substituted 2-benzylidene-1,3-dithioles and 2-benzylidene-1,3-diselenole, respectively. The maximum of the long wave-length absorption band of 3 varies from 580 nm up to 665 nm depending on the structure of the compound.The quantum yields of the photolysis of the diazonium salts 3 are low (1 · 10-4 to 7 · 10-3). The azo dyes obtained from 3 with usual azo-couplers absorb in a shorter wave-length range than the corresponding diazonium salts themselves (hypso-coupling effect).
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19903320106
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  • 9
    Digitale Medien
    Digitale Medien
    Lewis-Säure- und photochemisch induzierte Dimroth-Umlagerung von 3H,6H-2,5-Bis-(p-N,N-dimethylaminophenyl)-1,2-thiazolino[5,4-d]1,2-thiazolin-3,6-dithion (1990)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 332 (1990), S. 387-393 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Lewis-acid and Photochemically Induced Dimroth Rearrangement of 3H,6H-2,5-Bis-(p-N,N-dimethylaminophenyl) -1,2-thiazolino[5,4-d]1,2-thiazoline-3,6-dithioneThe reaction of 3H,6H-1,2-dithiolo[4,3-c]1,2-dithiole-3,6-dithione (5) with N,N-dimethyl-p-phenylendiamin gives, depending on the conditions of the reaction, 3H,6H-3-(p-N,N-dimethylaminophenyl-imino)-1,2-dithiolo[4,3-c]1,2-dithiole-6-thione (7), and 3H,6H-2,5-Bis-(p-N,N-dimethylaminophenyl) -1,2-thiazolino[5,4-d]1,2-thiazoline-3,6-dithione (3d). Catalyzed by Lewis acids the compound 3d rearranges reversibly into the isomeric 3H,6H-3,6-bis-(p-N,N-dimethylaminophenyl-imino) -1,2-dithiolo[4,3-c]1,2-dithiole (4d). The Dimroth type rearrangement of 3d into 4d occurs also on irradiation.
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19903320317
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  • 10
    Digitale Medien
    Digitale Medien
    Über die Thiocyanierung von AcetylendicarbonsäuredialkylesternI. Mitteilung der Serie „Organische Elektronenleiter und Vorstufen“ (1983)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 325 (1983), S. 153-156 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: About the Thiocyanation of Dialkyl Acetylendicarboxylates
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19833250119
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