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  • 29.40.Ym  (1)
  • Serum free insulin  (1)
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  • 1
    ISSN: 1432-0428
    Keywords: Serum free insulin ; insulin antibody ; binding constants ; highly purified porcine insulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifty-eight patients on long term conventional mainly bovine insulins have been transferred to highly purified porcine insulin preparations. There was an overall reduction of 22% in daily insulin dosage and improved diabetic control as shown by decreased blood glucose concentration. Increased concentrations of serum free insulin and falls in serum bound insulin levels were also found. There were reductions in the serum binding capacities and affinity constants on changeover from conventional to highly purified insulin due to a combination of the effects of differential conventional/purified porcine binding and the substitution of a low antigenicity insulin. However, 12 of the patients receiving higher doses of insulin experienced marked hypoglycaemic reactions immediately on insulin change-over despite initial dosage reductions of 30% and prior to any changes in antibody characteristics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of low temperature physics 93 (1993), S. 555-560 
    ISSN: 1573-7357
    Keywords: 74.40.+K ; 29.40.Ym
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Existing models show that any hotspot created in an Al film following a particle interaction is rapidly diluted. Quasiparticles and phonons decouple at high energies so that on short time-scales quasiparticle diffusion determines the energy transport. Few quasiparticles have energies near the energy gap and there is little gap suppression. We have measured the initial quasiparticle yields in very thin Al films and find somewhat surprisingly that this yield is reduced. It appears that a short time-scale quasiparticle loss mechanism, probably associated with localised over-injection, exists as quasiparticles scatter to low energies within the phonon hotspot.
    Type of Medium: Electronic Resource
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