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  • 1
    Electronic Resource
    Electronic Resource
    Tumor therapy and track structure (1999)
    Springer
    Radiation and environmental biophysics 38 (1999), S. 229-237 
    Details
    ISSN: 1432-2099
    Keywords: Key words Ions ; Tumor therapy ; RBE ; Track structure ; Treatment planning ; Carbon beam
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract  The elevated relative biological effectiveness (RBE) of heavy ions like carbon is the main reason for their use in radiotherapy and is due to the microscopic distribution of dose inside each particle track. High local doses produce lesions that are expected to have a diminished possibility of repair. Thus, RBE depends on track structure and on the biological repair capacity of the tissue that is affected by the irradiation. For tumor treatment planning with heavy ions, the beam quality and the tissue sensitivity have to be taken into account. Using the dependence of radial dose distribution on particle energy and atomic number on the physical side and x-ray dose response for the repair capacity on the biological side, the response to particle irradiation can be calculated in the local effect model (LEM) and used for treatment planning. This article traces the route from electron emission as the basis of track structure to the RBE calculation and the application in treatment planning.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004110050163
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Delta-electron emission in fast heavy ion — atom collisions: observations of new phenomena and breakdown of common scaling laws (1992)
    Springer
    The European physical journal 22 (1992), S. 713-721 
    Details
    ISSN: 1434-6079
    Keywords: 34.50.Fa ; 34.80.Kw
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Double differential cross sections for the emission of Delta-electrons have been measured in fast uranium-rare gas collisions. The well-known Binary Encounter peak reveals unexpected structures for certain observation angles and its intensity increases towards smaller angles, which is in contradiction to results and scaling laws obtained by experiments with light ion impact. The observed dependencies are fairly well described by recent calculations in the framework of IA and CTMC. From systematic experimental as well as theoretical studies we can derive that the potential of the partially stripped projectile ion gives rise to rainbow and glory scattering of the target electron in the field of the projectile. The rainbow scattering is observed in the laboratory frame as pronounced interference structures, whereas the glory scattering is responsible for the steep increase of the cross sections for binary-encounter electrons towards small laboratory ejection angles. The observed effects have a dramatic influence on the commonq 2 scaling laws derived from experiments with light ions. Furthermore, since the binary-encounter electrons ejected at forward angles have approximately twice the projectile velocity, these new phenomena have an important influence on the electronic stopping power of heavy ions and therefore have to be taken into account for the investigation of radiation damage by these ions e.g. in biological matter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01437253
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    Paper (German National Licenses)
    Fulltext
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