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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 60 (1982), S. 1357-1362 
    ISSN: 1432-1440
    Keywords: Gallbladder motor function ; Gallstone formation ; Gallbladder ultrasonography ; Gallbladder contraction ; Gallbladder refilling ; Gallensteinentstehung ; Gallenblasenkontraktion ; Motorische Gallenblasenfunktion ; Gallenblasenfüllung ; Ultraschalldiagnostik
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 8 Frauen mit stabilem Zyklus wurden mittels Sonographie das Gallenblasenvolumen bestimmt und in der Progesteron- sowie der Östrogenphase des Zyklus die Gallenblasenkontraktion nach oraler Reizmahlzeit und die spontane Wiederauffüllung der entleerten Gallenblase quantitativ untersucht. Zur Volumenberechnung wurde die Formel eines Drehellipsoids verwandt, die sich im Modellversuch als hinreichend exakt erwiesen hatte. Die intraindividuellen Vergleichsuntersuchungen zeigten in der Progesteronphase (21. oder 22. Tag) gegenüber der östrogenphase (12. oder 13. Tag) statistisch gesicherte größere Nüchternvolumina, höhere Residualvolumina nach Kontraktion und eine langsamere Gallenblasenentleerung sowie eine verzögerte Wiederauffüllung der entleerten Gallenblase. Dem hormonal modifizierten Kontraktionsverhalten und der unterschiedlich ablaufenden Gallenblasenfüllung könnte im Rahmen der Gallensteinentstehung eine wesentliche Bedeutung zukommen.
    Notes: Summary The gallbladder volume of eight women with stable cycles was determined by sonography. Furthermore, gallbladder contraction — following an orally administered fatty meal and the spontaneous refilling of the empty gallbladder — was quantitatively examined. The formula of a rotation ellipsoid, which has been proven to be adequately accurate in in vitro studies, was used for calculating the gallbladder volume. In the gestagen phase (21st or 22nd day) the intraindividual studies showed greater fasting volumes, higher residual volumes after contraction, slower gallbladder emptying, and retarded refilling of the empty gallbladder as compared to the estrogen phase (12th or 13th day). The hormonally modified contraction behavior and the differing course of gallbladder filling may play a major role in the pathogenesis of gallstone formation.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0649
    Keywords: 42.60 ; 42.55 ; 42.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We systematically investigate the difference between both actively and passively mode-locked lasers with Gain-at-the-End (GE) and Gain-in-the-Middle (GM) at the example of Nd:YLF lasers. The GE laser generates pulse widths approximately three times shorter than a comparable GM cavity. This is due to enhanced Spatial Hole Burning (SHB) which effectively flattens the saturated gain and allows for a larger lasing bandwidth compared to a GM cavity. We first investigate enhanced SHB by measuring the cw mode spectrum, where we have observed that the mode spacing in GE cavities depends primarily on the crystal length. This was also confirmed for a Nd:LSB crystal, where the pump absorption length was significantly shorter than the crystal length. In mode-locked operation, pulse widths of 4 ps for passive mode locking and 5 ps for active mode locking are demonstrated with GE cavities, compared to 11 ps for passive and 17 ps for active mode locking with GM cavities. Additionally, the time-bandwidth product for the GE cavity is approximately twice the ideal product for a sech2 pulse shape and cannot be improved by dispersion compensation alone, while the GM cavity has nearly ideal time-bandwidth-limited performance. The results for the GM cavity compare well to existing theories taking into account the added effect of pump-power-dependent gain bandwidth which increases the bandwidth of Nd: YLF from 360 to 〉 500 GHz. In a following paper [1] (called Part II) a rigorous theoretical treatment of the effects due to SHB will be presented.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 61 (1995), S. 569-579 
    ISSN: 1432-0649
    Keywords: 42.60 ; 42.55 ; 42.65
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In Part I of this paper [1] experimental results were presented and discussed. In this part, we investigate theoretically the dynamics of end-pumped solid-state lasers due to enhanced spatial hole burning. This becomes possible by a fast numerical implementation of the saturated gain in the presence of strong spatial hole burning that allows to treat the multimode case for an arbitrary pumping level. We find for a wide range of laser parameters that the mode spacing of the cw running modes is essentially determined by the length of the gain medium and only weakly depends on the absorption depth of the pump transition. It is shown that spatial hole burning can lead to a completely flat saturated gain profile over half of the gain bandwidth. In mode-locked lasers, the flat gain due to spatial hole burning results in shorter pulses. But the pulses are neither Gaussian-nor sech-shaped as they are in actively or passively mode-locked lasers without spatial hole burning. Further, we show that soliton-like pulse shaping can be used to restore a transform-limited sech-shaped pulse in an end-pumped solid-state laser while exploiting the full gain bandwidth of the laser material.
    Type of Medium: Electronic Resource
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