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Digitale Medien

Chemotherapy of autochthonous leukemias induced by 7,12-dimethylbenz(a)anthracene in long evans rats (1980)

Zeller, W. J. ; Berger, M. ; Schmähl, D.

Springer

Journal of cancer research and clinical oncology 96 (1980), S. 157-162

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Details

ISSN: 1432-1335

Schlagwort(e): Autochthonous (primary) rat leukemia ; 7,12 Dimethylbenz(a)anthracene ; Chemotherapy

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary A total of 111 autochthonous (primary) acute rat leukemias of the diffuse-hepatic type which had been induced by 7,12-dimethylbenz(a)anthracene were treated with mono- and combination chemotherapy. The survival time of treated rats increased significantly compared to untreated controls. A combination of vincristine (VCR), adriamycin (ADR), and cytosine arabinoside (Ara-C) was superior to a combination of VCR and ADR as well as to a monotherapy with Cyclophosphamide, BCNU, VCR, ADR, and Ara-C.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00405500

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