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  • Digitale Medien  (2)
  • 8α-amino-ergolines  (1)
  • Cytokinin  (1)
  • 1
    ISSN: 1420-9071
    Schlagwort(e): CQP 201-403 ; 8α-amino-ergolines ; ergot pharmacology ; D-2 agonist ; endocrine ; CNS ; cardiovascular actions
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The profile of action in animals of CQP 201-403, a novel 8α-amino-ergoline, is in most aspects that of a very potent dopaminomimetic, both as a prolactin secretion inhibitor, and at the levels of the CNS and the cardiovascular system. Qualitatively CQP 201-403 differs slightly from bromocriptine and apomorphine in its effects on the CNS (no influence on serotonin metabolism in the rat cortex; induction of masculine mounting behavior in rats) and the cardiovascular system of the dog (reflex tachycardia in response to a blood-pressure fall). In man the new compound proved to be highly active in lowering prolactin serum levels and to be more potent than bromocriptine (Parlodel®).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Plant growth regulation 32 (2000), S. 257-265 
    ISSN: 1573-5087
    Schlagwort(e): Anti-ageing ; Cytokinin ; Reactive oxygen species ; Hydroxyl radical. kinetin ; N6 – furfuryladenine ; Oxidative damage
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract In this paper we review the data on the structure and properties of N6-furfuryladenine (kinetin, K) accumulated during the last forty years. In 1955, kinetin was isolated from DNA as an artifactual rearrangement product of the autoclaving process. Subsequently, its cytokinin activity has been established, demonstrating a wide variety of biological effects, including those on gene expression, inhibition of auxin action, stimulation of calcium flux, the cell cycle, and as an anti-stress and anti-ageing compound. Recently, our views on this very well known plant hormone have changed. There are new data, which show that it occurs in cellular DNA as the product of oxidative, secondary modification and a secondary reaction of DNA. Also new results on the biological function of kinetin have been reported. Various biological effects produced by this hormone in vitro and in vivo have made kinetin even more scientifically interesting and commercially attractive as an ingredient of many beauty cosmetics.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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