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  • Acetylator phenotype  (1)
  • IMV (Intermittent Mandatory Ventilation)  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Methods of management of flail chest (1980)
    Springer
    Intensive care medicine 6 (1980), S. 217-221 
    Details
    ISSN: 1432-1238
    Schlagwort(e): Flail chest ; Pulmonary contusion ; IMV (Intermittent Mandatory Ventilation) ; PEEP (Positive End Expiratory Pressure)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We have treated 30 patients with flail chest, with priority given to associated factors (pain, secretions retention, hemo-/pneumothorax and underlying pulmonary contusion). When this treatment was insufficient IMV+PEEP was instituted; in this group there was a 58.8% incidence of pneumonia, 47.5% of sepsis and 11.7 days average stay in the ICU. These were significantly different when compared to the patients controlled without mechanical ventilatory support (7.7% pneumonia, 0% sepsis, 3.2 days). Surgical fixation was limited to 4 patients who presented with multiple and greatly displaced rib fractures, which made fixation by mechanical ventilation unpredictable.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01687161
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Acetylator polymorphism in rheumatoid arthritis (1993)
    Springer
    European journal of clinical pharmacology 45 (1993), S. 279-281 
    Details
    ISSN: 1432-1041
    Schlagwort(e): Rheumatoid arthritis ; Acetylator phenotype ; polymorphism ; sulphamethazine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary Acetylator phenotype has been determined with sulphamethazine (sulphadimidine) in 69 Spanish patients with rheumatoid arthritis (48 females), all of whom were on second line therapy, and in 96 age-matched normal controls (54 females). Thirty-two patients (46.4%) and 56 controls (58.3%) were classified as slow acetylators. On analysing separately the females in both groups, 37.5% of patients and 63% of controls were found to be slow acetylators. No difference was found in the males (patients 66.3% and controls 52.4% slow acetylators). Rapid acetylator phenotype may be a risk factor for the development of severe rheumatoid arthritis in women.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00315397
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
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