ISSN:
1432-1238
Keywords:
Left ventricular function
;
Wall stiffness and contractility
;
Acute myocardial infarction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract 10 patients with their first AMI were studied within the first 48 hours and again after 3 weeks. Central and peripheral haemodynamics (CI, SV, SW, TPR) were examined, including indices of contractility (dp/dlmax) and wall stiffness (ΔP/ΔV, relation ΔP/ΔV to P) of the left ventricle. In the early phase CI and SW, as well as LV dp/dtmax were depressed in accordance with symptoms of LV failure. ΔP/ΔV was increased. Elevation of LVEDP correlated well with ventricular gallop rhythm, but less consistently with LV functional disturbance. During convalescence CI increased uniformly, both in digitalized and non-digitalized individuals. In contrast heart rate, aortic pressure, LVEDP and dp/dtmax remained unchanged. The increase of CI, SV and SW was accompanied by a fall of TPR and ΔP/ΔV. LV wall stiffness was still elevated above normal after 3 weeks. The improvement of cardiac pumping during infarct convalescence may have been effected through a fall of TPR and LV wall stiffness. Recovery of depressed contractile performance was generally not observed, and does therefore not seem to contribute to recuperation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00571890
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