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Digitale Medien

Phorbol ester induces desensitization of PTH-stimulated cyclic AMP production by decreasing the PTH receptor binding in UMR-106 cells

Ikeda, K. ; Sugimoto, T. ; Fukase, M. ; [weitere]

Amsterdam : Elsevier

Biochemical and Biophysical Research Communications 176 (1991), S. 764-768

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ISSN: 0006-291X

Schlagwort(e): [abr] BSA; bovine serum albumin ; [abr] DMSO; dimethyl sulfoxide ; [abr] IBMX; isobutylmethylxanthine

Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Thema: Biologie , Chemie und Pharmazie , Physik

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1016/S0006-291X(05)80250-5

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Digitale Medien

Phorbol ester induces desensitization of PTH-stimulated cyclic AMP production by decreasing the PTH receptor binding in UMR-106 cells

Ikeda, K. ; Sugimoto, T. ; Fukase, M. ; [weitere]

Amsterdam : Elsevier

Biochemical and Biophysical Research Communications 176 (1991), S. 764-768

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Details

ISSN: 0006-291X

Schlagwort(e): [abr] BSA; bovine serum albumin ; [abr] DMSO; dimethyl sulfoxide ; [abr] IBMX; isobutylmethylxanthine

Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Thema: Biologie , Chemie und Pharmazie , Physik

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1016/S0006-291X(05)80250-5

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Digitale Medien

Dissociation of digoxin-like immunoreactivity and Na+,K+-ATPase inhibitory activity in rat plasma (1988)

Yamada, K. ; Goto, A. ; Ishii, M. ; [weitere]

Springer

Cellular and molecular life sciences 44 (1988), S. 992-993

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ISSN: 1420-9071

Schlagwort(e): Endogenous digitalis-like factor ; digoxin-like immunoreactivity ; Na+,K+-ATPase inhibitor

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary We measured endogenous digitalis-like factor (EDF) in rat plasma during acute saline infusion by two different procedures. Na+,K+-ATPase inhibitory activity in the rat plasma significantly increased during saline loading (7.8±2.2 vs 2.5±0.9%, with and without acute saline loading, respectively, p〈0.05). On the other hand, the plasma digoxin-like immunoreactivity significantly decreased during acute saline loading (16.9±1.6 vs 32.0±2.8 pg digoxin equivalents/ml. with and without acute saline loading, respectively, p〈0.01). These results indicate that the major substances detected by digoxin-like immunoreactivity and direct Na+,K+-ATPase inhibitory activity are completely different, at least in rat plasma.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01939897

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Digitale Medien

Further evidence for the dissociation of digoxin-like immunoreactivity from Na+, K+-ATPase inhibitory activity (1990)

Yamada, K. ; Goto, A. ; Ishii, M. ; [weitere]

Springer

Cellular and molecular life sciences 46 (1990), S. 1041-1043

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ISSN: 1420-9071

Schlagwort(e): Endogenous digitalis-like factor ; digoxin-like immunoreactivity ; Na+, K+-ATPase inhibitor ; adrenalectomy

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary The effects of adrenalectomy or nephrectomy, carried out one hour previously, on the levels of endogenous digitalis-like factors were determined in rat plasma. Factors were assayed by digoxin-like immunoreactivity and direct Na+, K+-ATPase inhibitory activity. Digoxin-like immunoreactivity significantly decreased one hour after bilateral ablation of adrenals, while Na+, K+-ATPase inhibitory activity remained unaltered. There were no changes in either activity one hour after bilateral nephrectomy. These results suggest that digoxin-like immunoreactivity may be derived from the adrenal gland or under adrenal control and the major substances detected by digoxin-like immunoreactivity and direct Na+, K+-ATPase inhibitory activity may be different.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01940667

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Digitale Medien

Quantitative analysis of a cross-sectional area of the optic nerve: A comparison between albino and pigmented rats (1984)

Sugimoto, T. ; Fukuda, Y. ; Wakakuwa, K.

Springer

Experimental brain research 54 (1984), S. 266-274

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ISSN: 1432-1106

Schlagwort(e): Optic nerve ; Fiber count ; Axon diameter ; Myelin sheath thickness ; Albino and gray rats

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Comparative studies were made on albino and gray rats by measuring several morphological characteristics seen in cross-sections of the optic nerve. The total cross-sectional area of the optic nerve was about 30% smaller in the albino than in the gray rat, while the fiber density was 1.4 times higher in the albino than in the gray rat. The estimated total fiber count was about the same in the two strains: around 100,000 to 110,000 fibers. Except for a few unmyelinated fibers (less than 1%) all fibers were myelinated. Axon diameters of the optic nerve fibers were distributed in smaller values for the albino than for the gray rat, though the overall diameter range was similar (0.2–3.0 μm). The myelin sheath was also thinner in the albino than in the gray rat.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00236226

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