Bibliothek

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Analytical Chemistry and Spectroscopy  (3)
  • SALMONELLA TYPHIMURIUM GLUTATHIONE  (1)
  • free radicals  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Intestinal mucosal lipid peroxidation and absorptive function In Salmonella typhimurium mediated intestinal infection (1998)
    Springer
    Molecular and cellular biochemistry 178 (1998), S. 345-352 
    Details
    ISSN: 1573-4919
    Schlagwort(e): Salmonella typhimurium ; brush border membrane ; lipid peroxidation ; free radicals ; antioxidants
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract S. typhimurium infection is associated with neutrophil infiltration within the intestinal mucosa. Neutrophil activation provides a major source of reactive oxygen species (ROS). The mucosal pathology of S. typhimurium infection may be in part due to the excessive production of these reactive species. This study was carried out to investigate if ROS play a role in mediating the changes in the structural components and functional properties of brush border membrane (BBM) in rats during S. typhimurium infection. This was done by determining the changes in the BBM extent of lipid peroxidation and absorptive function. A significant increase in the extent of lipid peroxidation of BBM during S. typhimurium infection was observed as judged by malondialdehyde (MDA) and conjugated diene formation and depletion of α-tocopherol and protein associated thiol groups. A significant decrease in the BBMV (brush border membrane vesicle) transport of amino acids was also observed. However there was no change in the transport of D-glucose. The decrease in amino acid transport further led to a significant decrease in the enterocyte level of protein synthesis. Exposure of BBMV to a free radical donor, cumene hydroperoxide, also led to an increase in the extent of lipid peroxidation and a decrease in the amino acid transport. Possibly ROS might play a significant role in mediating the mucosal damage during S. typhimurium infection.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1006891019115
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Impairment of Intestinal Mucosal Antioxidant Defense System During Salmonella typhimurium Infection (1998)
    Springer
    Digestive diseases and sciences 43 (1998), S. 646-651 
    Details
    ISSN: 1573-2568
    Schlagwort(e): ANTIOXIDANTS ; INTESTINE ; SALMONELLA TYPHIMURIUM GLUTATHIONE
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The mucosal pathology of Salmonella typhimuriuminfection may in part be due to the excessive productionof reactive oxygen species (ROS). The influence of S.typhimurium infection on the intestinal mucosal antioxidant defense system was investigated. Weinjected ligated rat ileal loops with Salmonella liveculture or toxin. After 18 hr of infection, the animalswere killed and enterocytes isolated from the ileal loops. The enterocyte-reduced glutathione(GSH) content and activities of the enzymes superoxidedismutase (SOD), glutathione peroxidase (GSH-Px),catalase, glutathione-S-transferase (GST), glutathione reductase (GR), and glucose-6-phosphatedehydrogenase (G6PDH) were spectrophotometricallyestimated. The vitamin E and A contents were determinedby high-performance liquid chromatography (HPLC). Inboth the Salmonella live culture and toxin-treatedgroups, the enterocyte GSH and vitamin E contents andactivities of the enzymes SOD, GSH-Px, catalase, GR, andG6PDH were significantly decreased as compared to the control group. However there was asignificant increase in the enterocyte activity of GST.There was no change in the vitamin A content of theenterocytes. These findings might indicate a decreased endogenous intestinal protection against ROS inS. typhimurium-mediated infection, which couldcontribute to the pathogenesis of the disease.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1018887813713
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Raman spectral studies of ion-molecular interactions of lithium bromide and lithium iodide with dimethyl sulphoxide (1989)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 20 (1989), S. 169-179 
    Details
    ISSN: 0377-0486
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: Raman spectra in the C—H and S=O stretching and S=O bending regions are reported for solutions of lithium halides and tetrabutylammonium bromide (TBAB) in dimethyl sulphoxide (DMSO) and DMSO-d6. The C—D stretching band of DMSO-d6 shows two components in solutions of TBAB with DMSO-d6, whereas the C—H stretching band of DMSO for solutions of LiX (X = Br and I) in DMSO show some broadening and asymmetry in the low-frequency region. The S=O stretching bands show changes in band shapes and band contours in solutions of electrolytes in DMSO. Fourier deconvolution of C—H and S=O stretching bands were carried out to gain more information regarding number of components present under the broad structured bands. All the solutions show a significant decrease in the intensity of the S=O bending bands when compared with the neighbouring C—S bending band. The results are discussed in terms of anion- and cation-molecular interactions with DMSO.
    Zusätzliches Material: 14 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jrs.1250200308
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 4
    Digitale Medien
    Digitale Medien
    Self-association of dimethyl sulphoxide and its dipolar interactions with water: Raman spectral studies (1984)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 15 (1984), S. 80-85 
    Details
    ISSN: 0377-0486
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: Raman spectra of solutions of dimethyl sulphoxide (DMSO) in carbon tetrachloride (CCl4) and water are reported for both parallel and perpendicular polarizations in the S=O stretching region. The various bands obtained were subjected to Gaussian band fittings. It was observed that the bands for solutions in CCl4 may be fitted satisfactorily by considering four components and those for solutions in water may be fitted by considering five components. It is inferred that the band at ca 1070 cm-1 observed in the spectra of DMSO in CCl4 belongs to the S=O stretching mode of free DMSO, whereas the two bands observed at ca 1058 cm-1 and ca 1040 cm-1 belong to out-of-phase and in-phase S=O stretchings of the cyclic dimer. The low-frequency band at ca 1025 cm-1 is assigned to linear dimer/higher polymers. Aqueous solutions of DMSO show an additional band at ca 1010 cm-1 due to DMSO hydrogen-bonded with water.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jrs.1250150203
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 5
    Digitale Medien
    Digitale Medien
    Raman spectral studies of aqueous solutions of non-electrolytes: Dimethylsulfoxide, acetone and acetonitrilePresented at 6th International Conference on Raman Spectroscopy, Bangalore, India (1978). (1982)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 13 (1982), S. 178-188 
    Details
    ISSN: 0377-0486
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: Raman spectra of aqueous solutions of dimethylsulfoxide, dimethylsulfoxide-d6, acetone and acetonitrile are reported in the OH stretching region, and in the stretching regions of the functional groups of these solutes. Raman intensities and frequency shifts of these bands show definite trends with varying concentrations of the solutions. The results obtained are discussed in terms of the mixture model of water, and they are compared with results obtained from Raman spectral studies of aqueous electrolytes. It is proposed that water structure breaking and the formation of solute-solvent complexes when organic solutes are added to water can account for these results.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jrs.1250130214
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...