ISSN:
1432-2072
Keywords:
Morphine
;
Anti-Nociception
;
Ouabain
;
Dopamine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Measurements of the anti-nociceptive activity of morphine were made in mice which had received intracerebroventricular injections of small doses of ouabain or dopamine, which were themselves devoid of anti-nociceptive activity. Both agents produced an immediate potentiation of the anti-nociceptive activity of morphine. Since centrally administered ouabain can increase whole-brain dopamine levels, it is possible that the observed potentiating effects of ouabain may involve a dopaminergic component.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00572268
Permalink