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  • 1
    Electronic Resource
    Electronic Resource
    Imaging of structures in the high-latitude ionosphere: model comparisons (1998)
    Springer
    Annales geophysicae 16 (1998), S. 969-973 
    Details
    ISSN: 0992-7689
    Keywords: Ionosphere (modelling and forecasting; polar ionosphere) ; Radio Science (instruments and techniques)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The tomographic reconstruction technique generates a two-dimensional latitude versus height electron density distribution from sets of slant total electron content measurements (TEC) along ray paths between beacon satellites and ground-based radio receivers. In this note, the technique is applied to TEC values obtained from data simulated by the Sheffield/UCL/SEL Coupled Thermosphere/Ionosphere/Model (CTIM). A comparison of the resulting reconstructed image with the ‘input’ modelled data allows for verification of the reconstruction technique. All the features of the high-latitude ionosphere in the model data are reproduced well in the tomographic image. Reconstructed vertical TEC values follow closely the modelled values, with the F-layer maximum density (NmF2) agreeing generally within about 10%. The method has also been able successfully to reproduce underlying auroral-E ionisation over a restricted latitudinal range in part of the image. The height of the F2 peak is generally in agreement to within about the vertical image resolution (25 km).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-998-0969-x
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  • 2
    Electronic Resource
    Electronic Resource
    Insulin and Hypersensitivity (1959)
    [s.l.] : Nature Publishing Group
    Nature 184 (1959), S. 2020-2020 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the first experiments, it was confirmed that intra-peritoneal injections of soluble insulin (4-12 units/ kgm.) given 15 min. before egg white (24 ml./kgm.) or dextran (300 mgm./kgm.) aggravated the anaphylac-toid reactions; its speed of onset was increased, and the reaction which developed was ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1842020a0
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  • 3
    Electronic Resource
    Electronic Resource
    Thyroid-adrenocortical Antagonism and Histamine Metabolism (1963)
    [s.l.] : Nature Publishing Group
    Nature 199 (1963), S. 1298-1299 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We have administered thyroxine sodium (1 or 2 mg/kg daily) to groups of rat and mice and then tested them for sensitivity to histamine. In all experiments, a temporary increase in sensitivity to histamine was noted, coupled with elevated tissue and urinary histamine. Continued treatment with ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1991298a0
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  • 4
    Electronic Resource
    Electronic Resource
    Phenylquinone Writhing Test : Interpretation of Data (1963)
    [s.l.] : Nature Publishing Group
    Nature 200 (1963), S. 895-896 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The in vitro anti-5-hydroxytryptamine activity of compounds was investigated using the isolated oestrus rat uterus preparation. Dose-response curves to 5-hydroxytryptamine (5HT) were obtained in the presence or absence of varying concentrations of antagonist and the concentration of antagonist ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/200895b0
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  • 5
    Electronic Resource
    Electronic Resource
    Ouabain and the Onset of the Blood-Brain Barrier in Neonate Chicks (1972)
    [s.l.] : Nature Publishing Group
    Nature 237 (1972), S. 513-514 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 Effect of age of young chickens on the response to peripherally-administered ouabain. Chicks received 0.7 mg/kg ouabain intraperitoneally (x) 2 days, (O) 3 days, (?) 4 days, (?) 5 days or (?) 10 days after hatching. In each case controls received 10 ml./kg saline intraperitoneally. Ranger ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/237513a0
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  • 6
    Electronic Resource
    Electronic Resource
    Modification of the anti-nociceptive activity of morphine by centrally administered ouabain and dopamine (1971)
    Springer
    Psychopharmacology 21 (1971), S. 111-117 
    Details
    ISSN: 1432-2072
    Keywords: Morphine ; Anti-Nociception ; Ouabain ; Dopamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Measurements of the anti-nociceptive activity of morphine were made in mice which had received intracerebroventricular injections of small doses of ouabain or dopamine, which were themselves devoid of anti-nociceptive activity. Both agents produced an immediate potentiation of the anti-nociceptive activity of morphine. Since centrally administered ouabain can increase whole-brain dopamine levels, it is possible that the observed potentiating effects of ouabain may involve a dopaminergic component.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572268
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  • 7
    Electronic Resource
    Electronic Resource
    Anti-nociceptive activity of narcotic agonists and partial agonists in mice given biogenic amines by intracerebroventricular injection (1975)
    Springer
    Psychopharmacology 42 (1975), S. 67-71 
    Details
    ISSN: 1432-2072
    Keywords: Narcotic Agonists/Partial Agonists ; Intracerebroventricular Injection ; Noradrenaline ; 5-Hydroxytryptamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using a tail immersion technique in mice, the anti-nociceptive activity of some narcotic agonists (diamorphine, etorphine, morphine and pethidine), partial agonists (cyclazocine, nalorphine and pentazocine) and naloxone have been determined alone, and after the intracerebroventricular (ICV) injection of 5-hydroxytryptamine (5-HT) or noradrenaline (NA). In common with morphine, the anti-nociceptive effects of each agonist and partial agonist studied were significantly increased by ICV 5-HT, and significantly attenuated by ICV NA. The marginal anti-nociceptive activity of naloxone was not significantly affected by the ICV injection ot either amine. It is concluded that the anti-nociceptive effects of all narcotic agonist and partial agonist agents are determined by the balance within the brain of the activities of the two amines, 5-HT and NA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00428828
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