ISSN:
1432-1440
Keywords:
Nausea and vomiting
;
Antiemetic agents
;
Cannabinoids, High-dosage metoclopramide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The present intensification of cancer chemotherapy has resulted in increased toxicity. Nausea and vomiting are often severe and prolonged, rendering a patient unfit for further treatment. This review summarizes the current understanding of the physiology of vomiting and the pharmacology and efficacy of the antiemetics in clinical use. It also discusses new approaches with agents, such as cannobinoids, high-dosage metoclopramide, and high-dosage corticosteroids. The new agents are superior to standard antiemetic drugs as demonstrated in a number of trials.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01726904
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