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  • 1
    ISSN: 1432-0533
    Keywords: Key words Pure autonomic failure ; Lewy bodies ; Autopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pure autonomic failure (PAF; also known as idiopathic orthostatic hypotension or Bradbury-Eggleston syndrome) is an uncommon sporadic disorder, characterized by autonomic failure without other neurological deficits and histopathologically by cell loss in intermediolateral columns and sympathetic ganglia. Few postmortem studies of patients with PAF have been reported in the literature, and none have demonstrated Lewy bodies in distal axons, although this has been described as a feature in Parkinson’s disease with autonomic failure. We report a patient with PAF who had orthostatic hypotension and urinary symptoms for 15 years prior to death at the age of 63 years. Postmortem findings included typical and atypical Lewy bodies in the substantia nigra, locus ceruleus, substantia innominata, and sympathetic ganglia, as well as in autonomic axons in the epicardial fat, autonomic nerve fascicles in periadrenal adipose tissue, and autonomic nerves in the muscularis of the urinary bladder. Sites of autonomic nerve involvement correlated with clinical symptomatology, and thus were a valuable observation in the complete autopsy. Systemic autopsy results should be reviewed carefully in patients with PAF, as Lewy bodies in this disease may be seen in distal axons at a great length from their primary cell bodies.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 337 (1974), S. 849-849 
    ISSN: 1435-2451
    Keywords: Vascular Injury ; Arterial Reconstruction ; Traumatic Ischemia ; Gefäßverletzung ; Arterienrekonstruktion ; Traumatisch bedingteIschämie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bericht über 314 Eingriffe am Arteriensystem nach Unfällen, davon 35 Aortenverletzungen. Unfallursachen: penetrierende, iatrogene, stumpfe Verletzungen, Verkehrsunfälle. Therapie: primär 40 Ligaturen, 9 Amputationen, 19 mal konservative Behandlung. 246 Arterien warden rekonstruiert. Ergebnis: 183 Rekonstruktionen zeigen gute, 18 eingeschränkte Funktion, 24 Patienten warden amputiert, 31 starben. — 28 Ligaturen zeigen gute Funktion, 5 schlechte Funktion, 6 Patienten warden amputiert, 1 starb. — Die konservativ Behandelten zeigen 9 mal gute, 5 mal eingeschränkte Funktion, 1 Amputation und 3 mal letalen Ausgang.
    Notes: Summary The report deals with 314 vascular operations after accidents, 35 of which involved aortic injury. Etiology: penetrating, iatrogennc, traumatic, following traffic accidents. Treatment: primary ligations in 40, amputation in 9, conservative treatment in 19 patients. Arterial reconstruction was performed in 246 cases. Results: 183 reconstructions resulted in good, 18 in limited function, 24 patients needed amputation, and 31 died. Twenty-eight ligations left good and 5 bad function, 6 patients needed amputation, and 1 died. Of the conservatively treated patients, 9 had good, and 5 had limited function, 1 required amputation, and 3 died.
    Type of Medium: Electronic Resource
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