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  • 1
    ISSN: 1433-0350
    Keywords: Iodine 125 ; Iridium 192 ; Diencephalon ; Astrocytoma ; Childhood ; Long-term results
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The only possible treatment of non-removable tumors of the diencephalon or recurring tumors invading the diencephalon after partial resection or percutaneous radiotherapy is interstitial irradiation (Curie therapy). With the CT/MRI stereotactic method, biopsy for histological tumor classification can be performed and 125I or 192Ir implanted, provided the neuroimaging methods show the delimitation of the tumor, its diameter does not exceed 3 cm and, given the patient's condition, focal irradiation seems advisable. As of 31 August 1987, a total of 1883 cases had been stereotactically biopsied and interstitially irradiated. The indications and results are reported in 204 patients under 18 years of age with diencephalic and deep-seated astrocytomas, after a follow-up period of up to 10 years; the data were compared for tumor resection, percutaneous irradiation, and for interstitial irradiation. The latter proved to be the most effective treatment.
    Type of Medium: Electronic Resource
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