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  • 1985-1989  (2)
  • Axonal degeneration  (1)
  • Hemisphere specialization  (1)
  • 1
    ISSN: 1432-0533
    Keywords: Isoniazid neuropathy ; Axonal degeneration ; Axonal swelling ; Paranodal demyelination ; Ventral root
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Morphometric sequential studies of pathologic changes were carried out on myelinated fibers in the lumbar ventral root of Sprague-Dawley rats administered with isoniazid, 1,500 mg/kg body weight, in a single dose. Accumulation of axoplasmic organelles with secondary paranodal retraction of myelin sheath occurred in the middle part of the ventral root as early as day 2 after the administration. On day 3, axonal degeneration started to occur, distal to the middle part, where the accumulation of axoplasmic organelles is prominent. Such accumulation with the possible blockade of the fast axoplasmic transport in the proximal axon may be directly responsible for the distal axonal degeneration. Alternatively such accumulation may be secondary to the distal axonal degeneration. The morphological sequential findings described clearly reflects the pathological events in isoniazid neuropathy.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1459
    Keywords: Cerebrovascular disease ; Micturition, frequency ; Hemiplegia ; Hemisphere specialization ; Micturition, urgency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To determine the individual contribution of the right and left cerebral hemispheres to micturition control, a clinical analysis was performed concerning frequency and urgency of micturition in 134 chronic hemiplegic patients. A mean frequency of urination, 9 times or more in 24h, was found more frequently in left than right hemiplegics. Left hemiplegics also complained more often of urgency than did right hemiplegics. A mean frequency of urination of 9 times or more in 24h and urgency co-existed more frequently in left hemiplegics than in right hemiplegics. In the present study, dealing with the chronic sequelae of stroke, frequency and urgency of micturition were found more commonly in patients with right hemisphere than left hemisphere lesions.
    Type of Medium: Electronic Resource
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