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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Medical & biological engineering & computing 30 (1992), S. 518-524 
    ISSN: 1741-0444
    Schlagwort(e): Blood flow in human limb ; Cross-sectional area ; Impedance plethysmography ; Strain gauge
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract The cross-sectional area of a limb varies along the extremity. This is of great importance when impedance plethysmography is used for limb blood flow studies. The actual measurement site, as well as the interelectrode distance, must be carefully selected to avoid underestimation of the blood flow value. The distance between the potential electrodes should be less than 10 cm for an adult subject.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Journal of neuro-oncology 10 (1991), S. 47-55 
    ISSN: 1573-7373
    Schlagwort(e): nitrosoureas ; glioma ; BCNU ; SarCNU ; PET ; chemotherapy ; brain tumor ; BBB
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary This paper describes the study of the pharmacodynamics of two 11C-labelled nitrosoureas, 1,3-bis-(2-chloroethyl) nitrosourea (BNCU) and sarcosinamide chloroethylnitrosourea (SarCNU), both labelled in the carbonyl position. Distribution of the radioactivity as measured by positron emission tomography was compared to the distribution of radioactivity observed after injection of 68Ga-EDTA, this being used as an indicator of the blood-brain barrier integrity around the brain tumor. Data suggest that the new nitrosourea, SarCNU, most likely enters brain tissue by different mechanism(s) than BCNU, which enters by diffusion. Data also indicate that use of SarCNU may result in a better tumor to brain ratio than BCNU.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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