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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 10 (1968), S. 356-358 
    ISSN: 1432-0533
    Keywords: Myelin ; Basic protein ; Encephalomyelitis ; Membrane asymmetry ; Allergy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Experimentelle Injektionsbehandlung von Meerschweinchen mit Extrakten aus der weißen Hirnsubstanz des Rindes ergaben, daß das encephalitogene Protein vorzugsweise oder ausschließlich in der anionen-empfindlichen Fraktion und im ionen-unempfindlichen Rückstand der Gehirnmarkscheiden verbleibt. Diese Lokalisation entspricht in den Myelinlamellen den Fortsetzungen der den intracellulären Raum begrenzende Plasma-membranen sowie den elektronenstrahlendichten Linien (dense lines) des Myelins.
    Notes: Summary Experiments on guinea pigs injected with extracts of bovine white matter have indicated that the encephalitogenic protein resides mainly, or only, in the anion-sensitive fraction and in the ion-insensitive residue of white matter myelin. In the myelin sheath structure this location corresponds to the continuation of layers of plasma membranes facing the intracellular space and to the dense lines of myelin in electron micrographs.
    Type of Medium: Electronic Resource
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