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  • Blood specimen collection  (2)
  • (Mammary epithelial cell)  (1)
  • 1
    ISSN: 0014-5793
    Keywords: (Mammary epithelial cell) ; Ca^2^+ activation ; Epidermal growth factor ; Hyperpolarization ; K^+ channel ; Membrane potential
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Comparative clinical pathology 4 (1994), S. 236-238 
    ISSN: 1433-2981
    Keywords: Blood coagulation ; Blood specimen collection ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Papers have recently been published regarding the acceptability of samples obtained from the orbital venous plexus for coagulation testing (Dameron et al. 1992; Edwards and Fuller 1993; Matsuzawa et al. 1994; Salemink et al. 1994). Meetings of the committee for International Harmonisation for Clinical Pathology Testing (IHCPT) have highlighted the concerns of sampling from the orbital venous plexus (OVP), both ethical considerations and validity of data. In response to a letter to the editor (Weingand, 1994) and to enable informed and objective discussion of this topic, this paper presents coagulation data on samples obtained from the OVP, collected by several pharmaceutical companies using a variety of systems.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Comparative clinical pathology 3 (1992), S. 40-42 
    ISSN: 1433-2981
    Keywords: Blood coagulation ; Blood specimen collection ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The UK Home Office currently advises that the amount of blood to be taken during a toxicology study is limited to 15% of an animal's blood volume (equivalent to approximately 1 ml per 100 g of the animal's bodyweight) in a 28 day period. At SmithKline Beecham, blood samples for routine haemtology and clinical chemistry analyses during a study have been obtained from the orbital sinus (OS). Adequate samples can be obtained for all routine assays with the exception of coagulation tests, and the possibility has been investigated of taking terminal coagulation samples from the posterior vena cava (PVC) as part of the post-mortem procedures, and compared the prothrombin (PT) and activated partial thromboplastin (APTT) times obtained on blood samples from each source. There was no biologically significant difference between samples taken from OS and PVC.
    Type of Medium: Electronic Resource
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